Janssen Pharmaceutica Nv

Gilbert A Grauwels

Raymond A Stokbroekx

Marcel G Luyckx

Marcel J Van Der Aa

Cyriel A Van Der Eycken

Intermediate for making 4-�2-Benzothiazolyl)methylamino!-alpha-�93,4-difluorophenoxy0methyl!1-pipe ridineethanol having the formula ##STR1##

Intermediates for making 4-�(2-benzothiazolyl)methylamino!-.alpha.-�(3,

A compound of formula ##STR1## the racemic mixture, the (S)-form and the acid addition salts thereof, said compound having anti-stroke properties. Pharmaceutical compositions containing this compound as active ingredient and a method of preparing said compound and pharmaceutical compositions.

4-[(2-benzothiazolyl)methyla

4-[(2-benzo

Novel pyridazinamine derivatives having antiviral activity, compositions containing these compounds as active ingredient, and a method of destructing viruses or preventing the growth thereof in warm-blooded animals suffering from diseases caused by these viruses. Processes for preparing said compounds and compositions.

Pridazinamine derivatives

Piperidinyl, pyrrolidinyl, azepinyl and piperazinyl pyridazines of formula ##STR1## wherein one or two carbon atoms of the ##STR2## moiety may be substituted with C.sub.1-4 alkyl, C.sub.1-4 alkyloxy or two carbon atoms of the CH.sub.2 groups of said moiety may be bridged with a C.sub.2-4 alkanediyl radical;

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Gilbert A Grauwels