Elan Pharma International Limited

Sanoculis Ltd.

Tel Hashomer Medical Research Infrastructure and Services Ltd.

Elan Corporation, Plc

Alkermes Pharma Ireland Limited

Elan Medical Technologies Limited

Nanopass Technologies Ltd.

Mininvasive Ltd.

Artack Medical (2013) Ltd.

Other

Teleflex Medical, Inc.

Drug Delivery Systems Inc.

Sid Technologies, LLC

Cytomedix, Inc.

Lapspace Medical Ltd.

Gilad Lavi

Izrail Tsals

Joseph Gross

Gil Yigal

Ehoud Carmel

Nir Israeli

Vadim Shmukler

Yoseph Glovinsky

Mordehai Sholev

Oz Cabiri

David Daily

Raphael Meloul

Yehoshua Yeshurun

Ronen Raz

Yotam Levin

Meir Hefetz

Zvi Nitzan

Yoel Sefi

Avi Azoulay

Nir Lilach

Eliahu Eliachar

Craig L Brodeur

Eran Shor

Haim Danon

Igor Igov

Hien Nguyen

Mario Rozanowich

Gilad Heftman

Jonatan Epstein

Israil Tsals

Assaf Livne

Gil Ygal

Maya Rosenblum

Ram Grossfeled

Miki Sahar

Jacob Stern

Diana Davidson

Mario Razonowich

Rami Lore

Udi Carmel

Mordechai Sholev

Yehushua Yeshurun

An apparatus for use in tissue removal from a body organ is presented. The apparatus comprises a hand-held probe device, a rotating motor device and a connection assembly configured for removably interconnecting between the hand-held probe device and the rotating motor device. The hand-held probe device is disposable and comprises a housing having proximal and distal ends, a rotatable cutting tool extending distally from the distal end of the housing and being configured for cutting and removing tissue during rotation, and a transmission assembly passing inside the housing between the proximal and distal ends and being configured for transmitting rotational power to the rotatable cutting tool. The connection assembly is configured for engaging between the rotating motor device and the transmission assembly to thereby controllably rotate the cutting tool and remove tissue. In some embodiments, the apparatus includes a control unit for controlling operation of the apparatus, the control unit comprises an activation mechanism for activating the rotatable cutting tool, and a controller configured for operating the activation mechanism to generate a single fixed activation signal of a known intensity and duration during a predetermined time interval, thereby restricting operation of the cutting tool during the time interval to the single activation signal only.

Apparatus for tissue removal

Medical devices and methods for removing a predetermined portion of soft tissue from a target tissue layer, thereby creating a channel between two side walls of the target tissue layer, are described. The medical device is a cutting tool comprising: an elongated round body extending along a longitudinal axis and having a uniform outer cross-section at a proximal side thereof; a cutting portion at a distal side of the elongated body, comprising at a distal end thereof a cutting edge of a first cross-section being smaller than said outer cross-section, and a distally and continuously decreasing outer cross-section; and a chamber extending along the longitudinal axis inside the cutting tool from said cutting portion, the chamber having dimensions enabling storing of the removed soft tissue portion inside the chamber thereby providing a validation to the channel creation.

Device and method for creating a channel in soft tissue

Medical devices and methods for removing a predetermined shape of soft tissue from a target tissue layer, thereby leaving a matching channel with predetermined geometry and orientation in the target tissue layer, are described. The medical device comprises coaxial outer and inner elongated members extending along axis X; said outer member comprises an open distal side and a first distal part configured for sticking to said target tissue layer during forward axial movement; said inner member comprises a second distal part configured to rotate and project distally through said open distal side to cut said predetermined shape of the soft tissue from the target tissue layer and create said channel formed as a hole across the target tissue layer.

The present disclosure provides medical devices for creating a channel in a biological soft tissue. The devices comprise an integral rotatable tool formed by an elongated distal member and a proximal shaft, the elongated member having a distal end portion and a proximal end portion, the distal end portion comprising a tissue piercing tip of a pyramid-like shape, and the proximal end portion comprising an elongated prism-like portion having at least three surfaces and respective prism edges, with at least one of the prism edges between the surfaces being configured as a tissue cutting blade, and the proximal shaft interfacing and extending from the prism-like portion and having a cross section larger than a cross section of the prism-like portion at the interface. In some embodiments, the device comprises an intermediate portion extending between the distal end portion and the proximal end portion and having a frustum shape, thereby forming a smooth transition between a base portion of the tissue piercing tip and the proximal end portion.

Medical device for tissue removal

Laparoscopic tool shafts and devices and methods for enhancing their rigidity in general or in specific directions are provided. Laparoscopic tool shafts having rigid external shafts and relatively rigid rods and laparoscopic tool shafts having flexible external shafts and relatively rigid rods are also provided.

Rigid and flexible laparoscopic tool shafts and methods using same

The present invention provides a circular bone tunneling device, comprising: a hollow elongate body comprising a hollow elongate body head, said hollow elongate body head defining a rigid circular arc, comprising a surgical needle; an extendable and retractable support element, reconfigurable from an extended configuration to a retracted configuration; said support element, in said extended configuration, adapted to be located along said path formed by said rigid circular arc; said support element and said hollow elongate body head are adapted to grasp said bone from at least two points along the circumference of said bone; a stabilizing element.

Circular bone tunneling device employing a stabilizing element

A tissue retractor device is provided. The tissue retractor device includes a handle attached to an inflatable rake-shaped tissue retractor head.

Tissue retractor

A fastening device, comprising an inner tube comprising a proximal end and a distal end and at least one fastener positioned within the inner tube and adapted to advance linearly towards the distal end of the inner tube, and an advancing element which converts rotational motion to linear pushing force on the fastener. In some embodiments of the invention, at least one fastener is adapted to not rotate at all or to rotate at a rate not necessarily the same as any other fasteners or any other elements during linear advancement.

Surgical fastening device and method

An adjustable suture passer for use in arthroscopic surgery is disclosed. In a preferred embodiment, the adjustable suture passer comprises a head that describes a semicircular arc, an elongate body, a support element, and driving and control mechanisms. The head is adapted to accommodate a surgical needle and a guide wire. When the adjustable suture passer is activated, the needle is driven with sufficient force to penetrate bone. Use of the adjustable suture passer thus enables surgical attachment of soft tissue to bone without any necessity for a separate anchor.

Circular bone tunneling device

An articulating medical instrument comprising of:

Articulating medical instrument

A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to undergo incremental advancement. The device may also be provided with manual control for delivering a bolus dose of drug when necessary.

Drug delivery device

A medical injection device is provided which includes a shield system and a syringe. The shield system includes a housing, a shield telescopically received in the housing and slidably coupled to the housing and a driver that pushes the syringe stopper to cause drug injection. The driver is equipped with sensing elements that automatically detect empty syringe. A spring resiliently urges the shield from a retracted position to an extended position shielding the needle. The syringe is coupled to the housing. The shield is positioned externally to the syringe and the driver. The shield includes flexible latches to keep its position relative to the housing during storage and use. The axial movement of the driver in respect to the syringe causes an automatic release of the spring by sensors when the syringe is empty, allowing the spring to move and lock the shield in the extended position after use.

Syringe with automatically triggered safety sleeve

Growing community of inventors

Rishon Lezion, Israel

Gilad Lavi