Ben-Gurion University of the Negev Research and Development Authority

Gil Shalev

In one aspect, the invention relates to an integrated circuit lab-on-chip bio-sensor, comprising: (a) a fluid compartment configured to receive a fluid; (b) a sensing layer at the bottom of the fluid compartment, the sensing layer has a top surface comprising molecules that are sensitive to target molecules of the fluid; (c) a readout structure in communication with the sensing layer, the readout circuit is configured to output a signal which is proportional to a sensing of target molecules by the sensing layer; and (d) at least one isolated electrode which is isolated from the fluid, the isolated electrode is configured to apply an electric field along at least an interface between the sensing layer and the fluid that in turn reduces or eliminates excess ion concentration along the interface during sensing.

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Ramat Hasharon, Israel

Gil Shalev