Centre National De La Recherche Scientifique

Gianfranco Pancino

Pierre Sonigo

Arthur Donny Strosberg

Giuseppe Bertoni

Pierre Sibille

Jennifer Richardson

Alexandre Avrameas

Anne Moraillon

Ernst Peterhans

The invention is drawn is to peptides encoded by the feline immunodeficiency virus (FIV) env gene and their immunoprophylactic applications (prevention and treatment of feline immunodeficiency). Said peptides, capable of inducing a certain degree of protection against FIV infection are selected from the group consisting of: peptides containing 12 to 19 amino acids which correspond to the following: Lys-Lys-Gly-Leu-Gln-Gln-Leu-Gln-Glu-Trp-Glu-Asp-Trp-Val -Gly-Trp-Ile-Gly-Asn (SEQ ID NO:1); and peptides of not more than 50 amino acids comprising said sequence set forth by SEQ ID NO:1.

Peptides derived from the ENV gene of the feline immunodeficiency virus and their applications

Mutated proteins encoded by a lentivirus mutated env gene, peptide

Nucleic acid fragments and corresponding peptide fragments from the

Specific peptide fragment from the feline immunodeficiency virus (FIV), and its use as a diagnostic reagent. The said peptide fragment, derived from the Env protein of the Wo strain of the feline immunodeficiency virus (FIV) (peptide P253), corresponds to positions 693-709 of the said Env protein and exhibits the following sequence: Leu-Gly-X-Asn-Gln-Asn-Gln-Phe-Phe-X-Lys-Val-Pro-Ser-Ala-, in which X represents a cysteine or a serine, as follows:

Specific peptide fragment of the feline immunodeficiency virus (FIV),

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Paris, France

Gianfranco Pancino