Siemens Healthcare Gmbh

Siemens Healthineers Ag

Gian Franco Piredda

Tobias Kober

Tom Hilbert

Lars Lauer

A system and a method for measuring a maturation stage of a biological organ are based on quantitative MR maps for the organ. The method includes acquiring with a first interface and for a subject, a quantitative MR map for the organ. The quantitative MR map includes voxels each characterized by a quantitative value. The quantitative value of each voxel represents a measurement of a physical or physiological property of a tissue of the biological organ for the voxel. The method also includes applying to the quantitative map a trained function to estimate the subject organ maturation stage, and the trained function outputting an age. The method provides with a second interface the maturation stage of the organ of the subject as being the output age.

Method and system for measuring a maturation stage using MRI

Organ tissue properties of a patient are automatically compared with organ tissue properties of a healthy subject group. A population norm for the organ tissue properties is determined by: selecting at least two different tissue properties of the organ; determining for each tissue property previously selected and for each subject of said group a quantitative tissue property map; for each subject of the group, calculating a joint histogram from all the quantitative tissue property maps obtained for said subject; and determining an averaged joint histogram from all subjects of the healthy group, thus defining the population norm. A comparison is automatically performed of the averaged joint histogram with a patient joint histogram obtained for the organ tissue properties of the patient, by calculating a statistical deviation of values of a patient joint histogram relative to values of the averaged joint histogram, and mapping the statistical deviation to the patient organ.

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Ecublens, Switzerland

Gian Franco Piredda