Intron Biotechnology, Inc.

Gi Mo Jung

SAng Hyeon Kang

Seong Jun Yoon

Soo Youn Jun

Jin Hee Lee

Jong Hyun Kim

Jee Soo Son

Hyoun Rok Paik

Myung Soo Kang

Sang Hyeon Kang

An antibacterial protein againstwith the amino acid sequence as set forth in SEQ ID NO: 1 is disclosed. Also disclosed is a method of preparing an antibacterial protein against. The method includes: culturing BL21-pBAD-BAL200 cells, the BL21-pBAD-BAL200 cells including a plasmid that comprising a sequence as set forth in SEQ ID NO: 2; inducing the expression of the antibacterial protein; and purifying the antibacterial protein.

Antibacterial protein having lytic activity togenus and method for preparing the same

The present invention relates to an antibacterial protein EFAL-2 derived from bacteriophage Ent-FAP-4 (Accession number: KCTC 12854BP), which has the ability to killand an amino acid sequence represented by SEQ ID NO: 2, a pharmaceutical composition containing the same as an active ingredient, and a method for preventing or treating diseases caused byusing the pharmaceutical composition.

Antibacterial protein EFAL-2 having bacteriolytic ability with respect to

A method of treating staphylococcal infections includes administering to a subject an effective amount of an antibacterial composition having a broad bactericidal activity. The antibacterial composition includes a first antibacterial protein consisting of the amino acid sequence as set forth in SEQ. ID. NO: 1 and/or a second antibacterial protein consisting of the amino acid sequence as set forth in SEQ. ID. NO: 2.

Antibacterial composition and a method of treating staphylococcal infections with the antibacterial composition

The present invention relates to a composition for improving the stability of bacteriophage originated lysin proteins greatly even when the composition contains the bacteriophage originated lysin proteins at a high concentration. More precisely, the present invention relates to a method and a composition for improving significantly the stability of SAL-1 or LysK, the bacteriophage originated lysin protein, included at a high concentration in the composition.

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Seoul, South Korea

Gi Mo Jung