Roche Molecular Systems, Inc.

Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Geza Burghardt

Rolf Schneebeli

Willem Mulder

Emad Sarofim

Pirow Engelbrecht

Andreas Gisler

Goran Savatic

Edwin Oosterbroek

Michael Glauser

Rijk Edwin Oosterbroek

David Tegerdine

Daniel Mueller

Oliver Gutmann

Hans-Rudolf Bachmann

Roger Sandoz

Kurt Barmettler

Nicholas Hastings

Daniel Müller

David Roger Tegerdine

A pipetting device () for an apparatus for processing a sample or reagent is disclosed. The pipetting device () comprises a coupling mechanism, wherein the coupling mechanism comprises at least a first coupling unit () adapted to be coupled to a first pipetting tip () and a second coupling unit () adapted to be coupled to a second pipetting tip (), and a selection element () for selectively allowing a coupling of the first coupling unit () to or releasing the first coupling unit () from the first pipetting tip () and for selectively allowing a coupling of the second coupling unit to or releasing the second coupling unit () from the second pipetting tip (). The selection element () is mechanically coupled to the first coupling unit () and the second coupling unit (). Further, an apparatus () for processing a sample or reagent and a method for pipetting a sample or reagent are disclosed.

Pipetting device for an apparatus for processing a sample or reagent, apparatus for processing a sample or reagent and method for pipetting a sample or reagent

A device, method and system is provided for binding particles for the separation and/or isolation of biological materials. In particular, a container is provided including a suspension of binding particles for the isolation of biological material, inner walls forming an elongate groove at the bottom of said container, and a cover having openings and/or being penetrable for a linear arrangement of multiple pipets or pipet tips, said openings being located above and parallel to said elongate groove.

Suspension container for binding particles for the isolation of biological material

An acceleration sensitive indicator for indicating a centrifugation status of a biological sample, a sample container comprising the indicator, a centrifuge for centrifuging samples and an analytical system for analyzing centrifuged samples are disclosed. The indicator comprises at least one closed chamber, formed between two opposite surfaces, that comprises an indication zone that comprises at least two fluid transfer zones or at least one particle transfer zone. The at least one fluid transfer zone comprises a solid carrier phase and a fluid stabilized in the solid carrier phase or at least one non-stabilized non-Newtonian fluid having thixotropic and/or shear thinning properties. The at least one particle transfer zone comprises a particle stabilizing fluid comprising stabilized dispersed particles. The fluid or particles have a distribution with respect to the indication zone changeable upon application of a g-force above a threshold value, the change of distribution indicating the centrifugation status.

Acceleration sensitive indicator

The present invention relates to a non-invasive method for surveilling mixing and separation of a suspension in an analytical system using solid phase particles for separation of an analyte by measuring particle distribution with a camera attached to a pipetting device.

Optical surveillance of mixing and separation

Growing community of inventors

Rotkreuz, Switzerland

Geza Burghardt