Lg Life Sciences, Limited

Lg Chem, Ltd

Lg Energy Solution, Ltd.

Geun Tae Kim

Tae Hun Kim

Ji Young Kim

Hye Jin Kim

Jong Sung Koh

Chang-Seok Lee

Hee Han

Hyun Jung Park

Heui Sul Park

Min-Jung Kim

Sung Pil Choi

Ki Dong Koo

Eun Sil Choi

Hyeon Joo Yim

Sung Ho Kim

Ki Sook Park

Sungsub Kim

Deok Seong Park

Sang Yong Hong

Vasily Artemov

Ki Chul Koo

Wan Su Park

Kyoung-Hee Kim

Seong Cheol Bu

Oh Hwan Kwon

Jeong Uk Song

Cheol Kyu Jung

Dong-Jun Yeo

Zi-Ho Yeom

Gwong-Cheung Hur

Dongchul Lim

Duck Il Yun

Hee Oon Han

The present invention relates to novel compounds which are effective as an inhibitor for xanthine oxidase, a process for preparing the same, and a pharmaceutical composition comprising a therapeutically effective amount of the same.

Compounds effective as xanthine oxidase inhibitors, method for preparing the same, and pharmaceutical composition containing the same

Novel compounds exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV(DPP-IV) include those of the following formula (1) or pharmaceutically acceptable salt thereof: wherein A is a substituted or unsubstituted 1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine, 5,6 -dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazine, 4,5-dihydro-7H-isooxazolo[3,4-c]pyridine, 3,4 -dihydroisoquinoline, 5,8-dihydropyrido[3,4-d]pyrimidine, or 6,7 -dihydro[1,3]thiazolo[4,5,c]pyridine, and B is a substituted or unsubstituted piperidin-2-one, morpholin-3-one, oxazolidin-2-one, pyrrolidin-2-one, or 1,5-dihydro-pyrrol-2-one. Methods of preparing the novel inhibitory compounds of formula (1) and pharmaceutical compositions containing the same as an active agent are disclosed.

Dipeptidyl Peptidase-IV inhibiting compounds, method of preparing the same, and pharmaceutical compositions containing the same as an active agent

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Daejeon, South Korea

Geun Tae Kim