I-sens, Inc.

Other

Geun Sig Cha

Infopia Co., Ltd.

Eyelab Group, LLC

I-sen, Inc.

Nano-ditech Corporation

Jihoon Kim

Hyun Ho Choi

Hakhyun Nam

Gang Cui

Moon Hwan Kim

Jae Ho Shin

Keun Ki Kim

Jae Hyun Yoo

Tae Young Kang

Joo Young Cho

Heejun Lee

Seok-Won Lee

Sung Dong Lee

Hak Hyun Nam

Joung Su Lee

Jong Sik Kim

Mark E Meyerhoff

Ji Hoon Wang

Goang Yel Ryu

Kyung Chul Chae

Myeongho Lee

Moon Hee Choi

Jeonghan Ha

Dongxuan Shen

Sung Hyuk Choi

Youngjea Kang

Jae Seon Lee

In Jun Yoon

Eun-Jong Cha

Kyung-Ah Kim

Sung-Kwon Jung

Jungwon Shin

Chang Woo Ryu

Ung Ki Lee

Jin Won Lee

Jin Seo Lee

Tae Eun Kim

Yong Suk Choi

Donald E Gillespie

Eun Jong Cha

Jina Yoo

In Seok Jeong

Junhee Han

Jae-hyun Yoo

Myeong-Ho Lee

Ho Dong Park

Kap Soo Park

Sung Pil Cho

Seung Hyun Jung

Bruce E Cohan

Hyo Jung Yoon

Byeong Woo Bae

Bo Kyeong Kang

Dong Hoon Han

Zvi Flanders

Fenghua Zhang

Mi Sook Park

Hyun Joon Oh

Jea Hun Song

Yeon Ho Jung

Da Yeon Sung

Min Woo Suh

Ju Yong Kim

Seung Hyeun Jung

Dong Kwon Lee

Seong Hee Oh

Myeong Ho Lee

Kyujeong Song

Seok Won Lee

Hyeong Eun Kim

Dae Kag Choi

Jun Hee Han

Hyung Jung Pyun

Eun Hye Im

Young Hoon Kim

Junho Chu

Joo-Heon Park

Hakhyum Nam

Soon Hye Yang

Keun-Ki Kim

Shim-Ho Lee

Sung-kwon Jung

Ung-Ki Lee

Hyo Lin Lee

Min Hyung Lee

Yeon-Ho Jung

Byung Wook Woo

Hyun Kyu Cho

Han-Be Park

Han Be Park

Sung A Hong

You Hwan Bae

Goang Yel Lyu

Display screen or portion thereof with virtual character icon

An apparatus for measuring a concentration of an analyte in a bio-sample using an electrochemical bio-sensor, includes a connector with a sample cell in which an oxidation/reduction enzyme and an electron transfer mediator are fixed and a working electrode and an counter electrode are provided; a digital-to-analog converter circuit configured to apply a constant DC voltage to start the oxidation/reduction reaction of the analyte, proceed with an electron transfer reaction, and apply a &#x39b;-step ladder-type perturbation potential for fluctuating a potential of the sample cell after applying the constant DC voltage; and a microcontroller configured to control the digital-to-analog converter circuit and directly obtain a concentration value of the analyte from a calibration equation using the &#x39b;-step ladder-type perturbation potential. The apparatus can improve measurement accuracy by effectively minimizing a matrix interference effect of a background material in a bio-sample, particularly an inaccuracy caused by a change in hematocrit.

Apparatus and method for measuring concentration of an analyte in bio-samples

The present invention relates to a kit for quantitative analysis of glycated hemoglobin (HbA1c), and the kit for quantitative analysis of HbA1c according to the present invention has excellent long-term stability of an enzyme reagent and thus has an effect of easily overcoming the disadvantages of the conventional reagents used in enzyme assays (e.g., storage, accuracy, portability, convenience of use, etc.).

Kit for hemoglobin A1C quantitative analysis

The present disclosure relates to an electron transfer mediator comprising the osmium complex or a salt thereof, a reagent composition for an electrochemical biosensor, and an electrochemical biosensor, where the osmium compound or its salt maintains a stable oxidation-reduction form for an extended time period, a capacity to react with oxidoreductase being capable of performing the redox reaction of the target analytes, and no effect of oxygen partial pressure.

Electrochemical biosensor

A method for measuring a concentration of an analyte in a bio-sample using an electrochemical bio-sensor according to an exemplary embodiment of the present invention is characterized by a step of obtaining predetermined features from induced currents obtained by applying a DC voltage according to chronoamperometry in which, after a whole blood sample is injected to the electrochemical bio-sensor, a concentration of an analyte is obtained from an induced current obtained by applying a DC voltage for a certain time and from all induced currents obtained by further applying several step-ladder perturbation potentials for a short time subsequent to the DC voltage for the certain time, and is also characterized by minimization of a measurement error caused by a hindering material by forming a calibration equation by combining the at least one feature in a function and optimizing various conditions of the bio-sample through DeletedTextsmultivariable analysis. With this configuration, a perturbation potential application method added to a conventional measurement method can maintain a bio-sensor and a measuring apparatus already used, a line used in the measuring apparatus, and calibration of amperometry as they are, improve accuracy in measurement by effectively minimizing a matrix interference effect of a background material in a bio-sample, particularly an inaccuracy caused by a change in hematocrit, and also remarkably improve accuracy in measurement by simply upgrading a measurement program of a conventional measuring apparatus.

Apparatus and method for measuring concentration of an analyte in whole blood samples

A portable blood glucose measurement device is provided. The device includes, in an externally exposed way, a temperature measurement medium of which the temperature quickly changes according to outside temperature changes provided on one side surface of a case. The device further includes an infrared temperature sensor. The device measures the temperature of the temperature measurement medium with the infrared temperature sensor in a noncontact manner, and calculates a blood glucose measurement result by considering the measured temperature so as to accurately reflect the outside temperature of an actual blood glucose measuring environment. The temperature measurement medium can be configured to sensitively respond to the outside temperature independently from the case such that the temperature of the temperature measurement medium, in accordance with the change in outside temperature, quickly and accurately changes so as to measure the temperature in a more accurate manner.

Portable blood glucose measurement device

The present invention relates to a stabilizing composition useful for improving the stability of reagent for redox reaction, and a reagent composition for redox reaction having an improved stability. The reagent composition for redox reaction can be applied for a reagent for electrochemical biosensor.

Reagent composition for redox reaction

A personal blood glucose meter and a method for sensing abnormal measurement using the same are disclosed. A personal blood glucose meter includes: a sensor strip for collecting and applying a blood sample, wherein the sensor strip includes a reagent; an electrode unit including a plurality of electrodes for receiving the blood sample from the sensor strip to generate electric current based on potential differences; an MCU for measuring currents value generated from the electrode unit to determine whether a glucose value of the blood sample is normal or abnormal; a potential supply unit for applying a predetermined potential to the electrode unit; and a display unit displaying resultant output from the MCU.

Personal blood glucose meter and abnormal measurement detection method using same

A composition of redox-reagent containing metal-containing complex and thionine or its derivative as electron transfer mediator for use in an electrochemical biosensor, and a biosensor containing the same are provided. With the increase in reaction rate between redox enzyme-thionine (or its derivative)-metal-containing complex in the composition of redox-reagent containing metal-containing complex and thionine or its derivative, glucose detection efficiency markedly increases, and the composition is hardly influenced from high humidity and interfering substances. Accordingly, the composition of redox-reagent is useful in fabricating an electrochemical biosensor for detecting glucose in blood.

Composition of redox-reagents for electrochemical biosensor and biosensor comprising the same

The present invention relates to an electrochemical biosensor with improved hematocrit measurement accuracy for measuring blood glucose. According to the present invention, an electrochemical biosensor including a first electrode part for correcting a measured hematocrit value and a second electrode part for measuring a glucose concentration is effective in improving accuracy of a measured hematocrit value and in more improving accuracy of a measured blood glucose concentration using the measured hematocrit values for correction, because an insulation cover is made thinner than a working electrode and an auxiliary electrode, so that areas of a first working electrode and a first auxiliary electrode of the first electrode part exposed to a blood sample become equal; a distance between the first working electrode and the second working electrode becomes constant; and electrode areas are maintained constantly by the insulation cover even when a positioning error occurs during printing.

Electrochemical biosensor with improved accuracy

Provided are an amperometric sensor and device for electrochemically quantifying nitrosothiol (RSNO), which is associated with storage and delivery of nitric oxide (NO) in the human body. The amperometric sensor for measuring a concentration of RSNO includes an electrode configured to measure an electric current generated by an oxidation reaction of NO, and a means configured to start and stop photo-induced decomposition of RSNO. Here, the electric current is measured by the oxidation reaction of NO before and after the photo-induced decomposition of RSNO. The amperometric sensor may measure separate signals of RSNO and NO, which are present in the sample at the same time, using one electrode, thereby preventing an inhibition action caused by NO during the measurement of RSNO. Also, the amperometric sensor is simple in structure and easy to manufacture and may be applied to manufacture of a small electrode, and thus may be developed as a sensor for in vivo measurements.

Amperometric sensors and devices for measuring concentration of S-nitrosothiols based on photo-induced decomposition of S-nitrosothiols

Disclosed is an electrochemical biosensor having a sample introduction channel in which an insulator is employed to introduce a small amount of a sample uniformly and accurately and to adjust an area of a working electrode, thereby guaranteeing the accurate quantitative analysis of a sample. Provided with a sample collection barrier at a sample entrance, the biosensor allows a sample to be introduced at higher accuracy and to be analyzed with higher reproducibility and reliability.

Electrochemical biosensor with sample introduction channel capable of uniform introduction of small amount of sample

The present invention relates to a cartridge for sensor for detecting the concentrations of one or more components in a sample. The cartridge for sensor for detecting one or more components in a sample of the present invention not only enables quantitative measurement of one or more components in a sample by one time sample injection but also facilitates mass-production with low cost owing to the simple structure and easiness in preparation and carry. Therefore, the cartridge of the present invention can be effectively used as the biosensor cartridge for field measurement.

Sensor cartridge for detecting component of at least one sample

Disclosed is a hemolysis reagent composition for the quantitative analysis of glycated hemoglobin (HbAlc) via an enzymatic method. The hemolysis reagent compositions of the present invention containing a zwitterionic surfactant and a nitrous compound considerably accelerate hemolysis rate due to the presence of the zwitterionic surfactant, and also induce the N-terminal &#x3b2;-chain of hemoglobin released by hemolysis to be exposed to the outside of the hemoglobin molecule and assists the participation of a greater number of molecules in the reaction, thereby improving reaction sensitivity and reaction rate of the glycated hemoglobin, and the nitrous compound makes the protein structure of the hemoglobin flexibly modified so that the amino acid sequence of the N-terminal &#x3b2;-chain of hemoglobin can be readily cut off, thereby significantly reducing the entire time required for the measurement and improving the accuracy of the measurement.

Hemolysis reagent composition for hemoglobin A1C quantitative analysis using enzymatic method

A lancet holder includes a holder body having a lancet seat at one end to mount a lancet and receiving the lancet and elastic fixing portions arranged in pairs to face each other on the inner side of the holder body so that the lancet received in the holder body is vertically held, and elastically fixing the lancet.

Lancet holder and lancet device including the same

Growing community of inventors

Seoul, South Korea

Geun Sig Cha