Elekta Ab

Forskarpatent I Linkoping Ab

Wheelsbridge Ab

Gert Nilsson

Folke Sjöberg

Karin W&aring;rdell

Ola Eriksson

This invention relates to the non-invasive determination of the degree of vasoactivity in the microcirculation in a tissue caused by a drug, disease, injury normal or pathological regulation. More specifically, the invention relates to a method of determining the influence on microcirculation in living tissue from an irritative agent, drugs, disease, injuries normal or pathological regulation including, illuminating a tissue surface with polarized light, collecting the backscattered light through a polarizing filter, detecting the backscattered and polarized light by a photo-sensitive array, transferring the collected information in digital form to a computing device, separating the collected information into at least two data matrixes, each representing a specific wavelength range and generating an output data matrix by processing corresponding values in at least two data matrixes by an algorithm, wherein each value in said output data matrix represents the amount of influence on the microcirculation in a source point of the tissue. Thereby a representation of the tissue microcirculation is obtained.

Non-invasive method to monitor microcirculation

The present invention relates to an apparatus for destroying a predetermined defined volume ( ) in a tissue, such as generating controlled coagulation, so-called lesion, in the brain. More particularly, the apparatus comprises a main unit ( ) for transmitting a tissue-destroying medium comprising a control unit ( ) for controlling the medium transmission, and a transferring means ( ), such as an electrode, which is connected to said main unit and adapted to be inserted into the predetermined volume for transferring the transmitted medium to the volume. The apparatus according to the invention is characterised in that it further comprises a measuring means ( ) for measuring at least one optical characteristic of the predetermined volume, the optical characteristic varying with the size of the destroyed volume, the measuring means being connected to said control unit for controlling the supply of the tissue-destroying medium on the basis of the measured optical characteristic.

Method and an apparatus for controlled destruction of tissue

Measuring of bloodgases

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Linköping, Sweden

Gert Nilsson