A. Nattermann & Cie Gmbh

A. Natternabb & Cie Gmbh

Gerrit Prop

Gerd Hilboll

Ille-Stephanie Doppelfeld

Hans-Heiner Lautenschlager

Jurgen Biedermann

Harald O Borbe

Erich Graf

Michael J Parnham

Ottfried Zierenberg

Hans Betzing

Sigurd Leyck

Andre Welter

Johannes Winkelmann

Josef P Lohr

Ferdinand Wirtz-Peitz

Helmut Wetzig

Axel Brekle

The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (.+-.)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl)-phenyl]-5-methyl-3(2H)-pyridazinone or 4,5-dihydro-6-[4-(1-imidazolyl)-thien-2-yl]-5-methyl-3(2H)-pyridazinone, on the other side, as the active substances.

Process for reducing reflex tachycardia in the treatment of hypertension

The present invention is directed to new, an imidazole group containing 2(1H)-pyridones of formula I ##STR1## salts thereof and process for treating congestive heart failure in humans.

Imidazole group containing 2(1H)-pyridones and method for treating heart

The invention refers to substituted 6-(thien-2-yl)-3(2H)-pyridazinones of Formula I ##STR1##

Substituted 6-(thien-2-yl)-3(2H)-pyridazinones

The invention is related to imidazol-2-yl mercapto alkanoic acids having the formula I ##STR1## process for the treatment of humans suffering from inflammatory diseases or diseases in relation with the lipid metabolism.

1,4,5-triphenylimidazol-2-yl mercapto alkanoic acids, useful against

The invention relates to new imidazolylalkylthienyltetrahydropyridazines of the general formula I ##STR1## their acid addition salts as well as processes for their use in the treatment of cardiovascular and/or thromboembolic illnesses in humans.

Imidazolylalkylthienyl tetrahydropyridazines and processes for their use

The invention is related to 1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids having the formula I ##STR1##

1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids

The invention concerns new substituted aminoalkanol phospholipids of the general Formula I ##STR1## and methods for the treatment of humans suffering from high blood-pressure (hypertension), from inflammatory illnesses, from tumors and/or atherosclerosis by administering medicaments containing such a compound as well as methods for plant protections.

Substituted aminoalkanol phospholipids

The present invention relates to new O-alkyl-O-carbamoylglycerophosphocholines of the general formulae I or II ##STR1## and processes for treating human beings suffering from diseases caused by hypertension by administering one or several of the above compounds.

O-Alkyl-O-carbamoylglycerophosphocholines and the use for treating

The present invention relates to new 6-[Imidazolyl-phenyl]-5-methyl-3-oxo-tetrahydropyridazines of the general formula I ##STR1## as well as their acid addition salts, methods for their use, and pharmaceutical preparations containing them.

Method of treating high blood pressure using

This invention relates to processes for producing the (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for lowering the blood pressure in human beings suffering from increased blood pressure, using these compounds.

Process for producing

The invention relates to new triphenylimidazolyloxyalkanoic acids of the general formula I ##STR1## and a process for the treatment of thromboembolic, inflammatory and/or atherosclerotic diseases in humans by using the same.

Triphenylimidazolyloxyalkanoic acids and their derivatives and a process

This invention relates to (+)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for the treatment of human beings suffering from nervous disarrangements, in particular migraine, using these compounds.

Growing community of inventors

Pulheim, Germany

Gerrit Prop