B. Braun Melsungen Ag

Gerold Morsch

Dietrich Seidel

Karl-Siegfried Boos

Annette Trautwein

Wolfgang Feller

Gudrun Henke

Andreas Rauh

Waltraud Sichler

Susan Koch

In order to remove tumor necrosis factor .alpha. (TNF.alpha.) or/and bacterial lipopolysaccharides (LPS, endotoxin) extracorporeally from whole blood or/and blood plasma in an extracorporeal perfusion system, the blood or plasma is passed over a cation exchanger and an anion exchanger material. A device according to the invention for the extracorporeal treatment of patient's blood or plasma therefore contains a cation exchanger material and an anion exchanger material wherein these materials are contained in at least one compartment of an extracorporeal perfusion system.

Process and device for the simultaneous extracorporeal elimination of

Disclosed is a process to remove tumour necrosis factor .alpha. (TNF.alpha.) or/and bacterial lipopolysaccharides (LPS) from an aqueous liquid, in particular blood, blood plasma or serum, in an extracorporeal perfusion system after removing corpuscular blood components if necessary, wherein (a) the pH value of the body fluid is adjusted to pH&lt;6, (b) a precipitation reagent in the form of a polyanion is added, (c) precipitated substances are removed by filtration or/and centrifugation and (d) the resulting liquid is passed over an anion exchanger.

Process for simultaneously removing tumour necrosis factor .alpha. and

Adsorption material for the selective removal of LDL and/or vLDL and

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Willinghausen, Germany

Gerold Morsch