Basf Aktiengesellschaft

Gernot Reissenweber

Winfried Richarz

Knut Koob

Eberhard Ammermann

Hubert Sauter

Ulrich Schirmer

Dietrich Mangold

Bernd Schaefer

Siegfried Kersten

Bruno Wuerzer

Gerhard Hamprecht

Norbert Goetz

Karl Eicken

Ernst-Heinrich Pommer

Peter Plath

Wolfgang Rohr

Toni Dockner

Ernst Buschmann

Volker Maywald

Norbert G&ouml;tz

Dieter Jahn

Friedrich Linhart

Eckhard Hickmann

Hans Rupert Merkle

Peter Schaefer

Horst Hartmann

Lothar Rueb

Manfred Sauerwald

Heinz Eckhardt

Peter C Thieme

Guenter Schulz

Bjoern Girgensohn

Albrecht Mueller

Hartmann K&ouml;nig

Guenter Retzlaff

Walter Ditter

Peter Jacobs

Joseph Krug

Detlef Doehnert

A process for removing impurities from 3-(2&prime;-acetoxyethyl)dihydro-2(3H)furanone (I), where the 3-(2&prime;-acetoxyethyl)dihydro-2(3H)furanone containing the undesirable impurities is initially prepared in a manner known per se by acetylation of 3-(2&prime;-hydroxyethyl)dihydro-2(3H)furanone and the resulting product is subsequently subjected to a distillation or rectification, includes carrying out the distillation or rectification in a plurality of steps, where high-boiling impurities are removed in a first step, the product which is drawn off via the top is subsequently subjected to at least one further step in which low-boilers and intermediate boilers are drawn off via the top and the desired pure I is obtained as bottom product.

Removal of impurities from 3-(2&prime;-acetoxyethyl)-dihydro-2(3H)furanone

A process for the preparation of &agr;-chloromethylene-triorganylphosphorane derivatives I

Process for the preparation of &agr;-chloromethylene-triorganylphosphorane derivatives

The manufacture of 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo�4.3.0!-nonane I by the reaction of 3,3,6-trimethyl-9-oxo-1,5-diaza-bicyclo�4.3.0!nonane II with dichloroacetyl chloride in the presence of a solvent and a base, wherein

Process for the manufacture of

.alpha.,.beta.-Unsaturated ketones of the general formula I ##STR1## where R is an organic radical, are prepared by reacting a corresponding aldehyde R--CHO with acetoacetic acid or one of its salts in the presence of an amine in a two-phase reaction mixture by a process in which the reaction is carried out at a pH of from 6 to 8 in the presence of a catalytic amount of a primary amine.

Preparation of .alpha.,.beta.-unsaturated ketones

Process for making 3,4,5,6-tetrahydrophthalimide derivatives

Process for the purification of 7-chloroquinoline-8-carboxylic acids

A process for the preparation of cyclohexanedione derivatives of the general formula I ##STR1## where R.sup.1 is C.sub.2 -C.sub.8 -alkyl, C.sub.2 -C.sub.8 -alkenyl, C.sub.3 -C.sub.12 -cycloalkyl, C.sub.5 -C.sub.12 -cycloalkyl with 0-4 olefinically unsaturated bonds, C.sub.2 -C.sub.8 -alkylthioalkyl, C.sub.6 -C.sub.12 -bicycloalkyl with 0-3 olefinically unsaturated bonds, unsubstituted or substituted aryl or hetaryl, or a heterocyclic radical of 4 to 7 atoms of which not more than 3 may be hetero-atoms chosen from O, S and N, the radical being saturated or olefinically unsaturated, by reacting an .alpha.,.beta.-unsaturated ketone (II) with a dialkyl malonate in the presence of a base to give the alkoxycarbonylcyclohexenolone or its salt (III) ##STR2## and acylation, hydrolysis and decarboxylation of (III), wherein the .alpha.,.beta.-unsaturated ketone (II) is reacted, in the presence of a base, with the dialkyl malonate in a solvent from which the alcohol liberated from the malonate can be distilled off, the alcohol is distilled off, where appropriate as an azeotrope, the salt of the alkoxycarbonylcyclohexenolone is reacted with a carboxylic acid halide and the product, where appropriate after removal of excess acyl halide, is treated with an acylation catalyst, hydrolyzed and decarboxylated.

Preparation of heterocyclic-cyclohexanedione derivatives

Preparation of cyclohexane-dione derivatives

A batchwise or continuous process for separating water from a mixture of water and 1-methoxy-2-propanol by passing a heated mixture in liquid or gaseous form over a hydrophilic membrane which is selective to the passage of water.

Separation of 1-methoxy-2-propanol and water

A process for the preparation of N-phenyl(pyridyl)sulfonyldiamides by reacting a 2-aminobenzoic acid (nicotinic acid) derivative with sulfur trioxide, chlorosulfonic acid or an adduct of sulfur trioxide with a tertiary amine in the presence of a diluent and of a tertiary amine, and reacting the resulting sulfamate with a primary amine and a phosphorus halide, or by reacting a 2-aminobenzoic acid (nicotinic acid) derivatives with an N-alkyl(cycloalkyl)sulfamic acid or a salt of this acid in the presence of a diluent and of a phosphorus halide.

Preparation of N-phenyl(pyridyl) sulfonyldiamides

Pyridazinone derivatives of the formula ##STR1## where R.sup.1 is alkyl, alkenyl, cycloalkyl or unsubstituted or substituted phenyl, R.sup.2 is chlorine or bromine, R.sup.3 is hydrogen, alkyl, cycloalkyl or unsubstituted or substituted phenyl and X is SO or SO.sub.2, with the proviso that R.sup.1 is not methyl when X is SO.sub.2, R.sup.2 is chlorine and R.sup.3 is phenyl, and fungicides containing these compounds.

Pyridazinone derivatives and their use as fungicides

O-(1-Methoxy-2-chloro)ethoxyphenyl N-methylcarbamate is prepared by reacting pyrocatechol carbonate with methylamine and then reacting the resulting pyrocatechol monomethylcarbamate with 1,2-dichloroethyl methyl ether in the presence of a secondary amine.

Preparation of o-(1-methoxy-2-chloro)-ethoxyphenyl N-methylcarbamate

Sterically pure .beta.-triazolyl carbinols of the general structure ##STR1## where R is not hydrogen, in particular the R*, S*-diastereomer, are obtained by diastereoselective reduction of the corresponding .alpha.-triazolylketone with a complex hydride which reduces ketones to alcohols, in the presence of a Lewis acid in a non-polar solvent.

Diastereoselective reduction of alpha-triazolylketones to

5,6-Dihydro-2H-thiopyran-3-carboxaldehydes of the formula ##STR1## where R denotes hydrogen or methyl, are prepared by a method in which acrolein or crotonaldehyde is reacted with hydrogen sulfide in a mineral oil whose boiling point is higher than those of the starting materials and of the end product, and the 5,6-dihydro-2H-thiopyran-3-carboxaldehyde is obtained by distillation. These aldehydes are important intermediates for the preparation of some crop protection agents.

Process for the preparation of 5,6-dihydro-2H-thiopyran-3-carboxaldehyde

3-Formyltetrahydrothiopyrans are prepared by hydrogenating a 3-formyl-5,6-dihydro-2H-thiopyran in the presence of a catalyst containing nickel, cobalt, platinum, copper and/or silver; if necessary, the 3-formyl-5,6-dihydro-2H-thiopyrans are prepared by converting bis-(.beta.-formylethyl) sulfides and/or 3-formyl-4-hydroxytetrahydrothiopyrans in the presence of an acidic catalyst, and, if required, these bis-(.beta.-formylethyl) sulfides and/or 3-formyl-4-hydroxytetrahydrothiopyrans are prepared by reacting an acrolein with hydrogen sulfide (a) in the presence of a basic catalyst and of methylene chloride, aromatic hydrocarbons and/or 1,1,2-trichloroethane as solvents, and/or (b) in the presence of a carboxamide. The compounds obtainable by the process according to the invention are useful starting materials for the preparation of dyes, drugs and pesticides.

Preparation of 3-formyltetrahydrothiopyrans

Growing community of inventors

Boehl-Iggelheim, Germany

Gernot Reissenweber