Albert Rolland S.a.

Albert Roland S.a.

Germaine Thuillier, Nee Nachmias

Pierre A Bessin

Jacqueline S Laforest, Nee Boutillier Du Retail

Jean Eugene Thuillier

Bernard J Cariou

Jacqueline S Bonnet, Nee Roux

Sylviane S Mignonac, Nee Mondon

The invention provides certain 4-keto-phenoxyacetic acids and their oximes of the formula: ##STR1## in which A is selected from oxygen and sulphur,

4-Keto-phenoxyacetic acids

Compounds of the general formula I ##STR1## wherein n represents 0, 1 or 2, A represents oxygen or sulphur, Z represents oxygen or hydroxyimino, X represents hydrogen, or halogen, the dotted lines represent bonds which may be unsaturated or saturated, R.sub.1 and R.sub.2 each represent hydrogen or alkyl, and R.sub.3 represents hydrogen, halogen or methyl, and R.sub.4 represents a hydrogen atom, or R.sub.3 and R.sub.4 together with the two carbon atoms to which they are attached represent benzene, and their pharmaceutically acceptable salts are useful in therapy, in particular as uricosuric agents or as diuretic and uricosuric agents.

Furoyl- and thenoyl-aryloxyalkyl carboxylic acid derivatives, their

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Paris, France

Germaine Thuillier, Nee Nachmias