Korea Electrotechnology Research Institute

Geri V Papayan

Uk Kang

Soo Jin Bae

Guang Hoon Kim

Geun Hie Rim

A system is provided for photodynamic diagnosis and therapy of skin diseases. In particular, a camera head is provided to irradiate a white light, a fluorescent excitation light and a therapeutic light for the photodynamic therapy from the inside of a case onto the skin region being in contact with a view hole. Additionally, a digital color TV camera collects the light from the skin region and outputs a generated image signal. In particular, an image processing and analysis system receives the image signals from the camera head to process, analyze and store the same, displays a color image by the white light, a fluorescent image by the excitation light and the therapeutic light for the photodynamic therapy, obtained by the digital color TV camera, and a synthesized image thereof, and controls the general operations of the camera and the light source system.

Apparatus and method for photodynamic diagnosis and therapy of skin diseases and light source system thereof

Disclosed herein is an apparatus for and method of measuring bio-chips, which can implement an illumination method of a novel type that illuminates a bio sample (which may be also referred to as a 'bio specimen') through a side face of a substrate using a diffusion plate to form an evanescent field by the illumination light over the entire surface of a substrate so as to uniformly secure brightness of the illuminated light over a wide area of a substrate, thereby more efficiently measuring fluorescence information of a bio-chip over a wide field of view.

Apparatus for and method of measuring bio-chips using uniform total internal reflection illumination

The present invention provides an apparatus for white light observation and fluorescence diagnosis of skin diseases. More particularly, the present invention provides an apparatus for photodynamic diagnosis in which a plurality of excitation light emitting diodes (LEDs) is provided in an image pick-up head, the excitation LEDs being arranged to illuminate the entire examination region in the form of a mosaic by setting respective illumination light axes of the excitation LEDs to illuminate preassigned individual areas of the examination region, thus uniformly illuminating the examination region in a wide field of view with excitation light. In the apparatus for photodynamic diagnosis, the respective excitation LEDs are provided at the same or different angles based on the light axis of the object lens, and thereby it is possible that the beams of the light sources composed of the LEDs illuminate the field of view of the examination region uniformly, thus improving the uniformity of illumination. Moreover, the present invention provides an apparatus for photodynamic diagnosis in which warm white LEDs and cold white LEDs as white light sources are appropriately arranged so as to deliver natural colors and thereby to reproduce natural color images.

Growing community of inventors

Saint Petersburg, Russia

Geri V Papayan