Barry University, Inc.

Hansen Pharmaceutical, LLC

Gerhild Packert

Christopher C Miller

Jeffrey L Jensen

Daniel Packert

Alex Stenzler

Frank J McCaney

Embodiments of the present disclosure provide systems and devices for delivering gaseous Nitrous Oxide (gNO) under therapeutic parameters to reduce infection in a subject. Certain embodiments include devices and systems for delivering pressurized gNO to reduce bioburden and promote healing in the wounds of subjects having various disease conditions, including skin and soft tissue infections (SSTIs) and osteomyelitis. In some embodiments, the present disclosure provides portable wound healing devices for delivering pressurized gNO to the site of a wound to treat various disease conditions in a subject.

Nitric oxide delivery system and methods of use

The present invention provides methods of treatment by delivering nitric oxide at a pressure greater than 1 atmosphere (atm) to a subject in need thereof. Thus, the present invention provides an improved method of treating the skin surface of a subject, and below the skin surface of a subject.

Methods of treatment with nitric oxide at pressures greater than one atmosphere

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Pembroke Pines, FL, United States of America

Gerhild Packert