Bayer Aktiengesellschaft

Agfa-gevaert Ag

Miles Inc.

Miles Laboratories, Inc.

Afga-gevaert Aktiengesellschaft

Gerhard Wolfrum

Herbert Hugl

Richard Sommer

Peter Bergthaller

Holger Heidenreich

Gunther Schenk

Dieter Vor Der Bruck

Karl H Schundehutte

Hans-Gunter Otten

Hans-Volker Runzheimer

Kersten Trautner

Erich Klauke

Gerhard Buttner

Rudolf Stolzenburg

Jurgen Strauss

Albrecht Marhold

Klaus Wehling

Georg Rainer

Winfried Mennicke

Karl-Heinz Schundehutte

Eugen Schnabel

Robert Kuth

Dietmar Kalz

Walter Horstmann

Werner Kuhnel

Klaus-Friedrich Lehment

Henning Reel

Heinrich Gold

A Christopher Skjold

Karl-Ludwig Moritz

Jochen Westphal

Edgar Siegel

Wilhelm Gohrbandt

Hans Gunter Otten

Hans Trautwein

Werner Kunnel

A method for detecting hydrogen peroxide wherein a sample is contacted with a peroxidase or a peroxidatively-active substance and a redox indicator of the following ##STR1## in which A and D independently of one another represent phenyl, pyridyl or imidazolyl,

Method for detecting hydrogen peroxide employing triaryl- and

The present invention relates to new chromogenic amino acid esters and peptide esters of hydroxyisoquinolines and hydroxyquinolines, processes for their preparation and the use of the new esters as substrates for the analytical detection of esterolytic and/or proteolytic enzymes, for example in body fluids, the esters being incorporated into test agents, in particular test strips, in a suitable manner. The new esters are particularly used for the detection of leukocytes, in particular in urine.

Method for detecting esterolytic and proteolytic enzymes

Azo dyestuffs of the formula ##STR1## wherein R.sub.1 denotes acyl,

Orthotrifluoromethyl containing phenylazonaphthol dyestuffs

4-Alkyl-2-trifluoromethylanilines, in particular the 4-isopropyl derivative, are starting materials for preparing valuable azo dyestuffs. While the nonionic dyestuff types can preferably be used in transfer printing synthetic hydrophobic fibre materials, the sulpho-containing dyestuffs--in particular those based on 'gamma acid'--are suitable for dyeing polyamides.

4-alkyl-2-trifluoromethylanilines

Azo dyestuffs which contain at least one water-solubilizing group and have the formula ##STR1## wherein K stands for the radical of a coupling component,

3-thienylazo dyes with a gamma-acid coupler

A composition and test device for determining the presence of an analyte selected from leukocytes, esterase and protease in a test sample. The composition comprises an ester capable of producing a detectable response upon interaction with said analyte, and a diazonium salt having the structure ##STR1## in which A.sup.- is an anion, and R same or differ, is H, lower alkyl, aryl, or both of R together form a fused ring system, and in which R' is H, OH or lower alkyl.

Composition and test device for determining the presence of leukocytes

Metal complexes, particularly copper and nickel complexes of azo dyes corresponding to general formula (I) are suitable as color dyes for the production of color images by the dye diffusion transfer process. The dyes are (in non-metallized form), in the form of so-called 'dye-releasers', bound to a redox-active carrier radical provided with a ballast group, which dye-releasers are associated to a light-sensitive silver halide emulsion layer. During development, the metallizable dyes are image-wise released and are converted, after diffusion into a light-receiving layer, into the corresponding metal complexes ##STR1## wherein E represents an electron acceptor radical; and

Color photographic material with azo dicyanoimidazole dyes

Dyes corresponding to general formula (I) are released imagewise from corresponding dye-releasers in the dye diffusion transfer process. They react with nickel ions to form lightfast, cyan dye-metal complexes having advantageous spectral properties: ##STR1## wherein Q represents the group required for completing an optionally substituted phenyl or naphthyl group;

Color photographic recording material containing dye-releasers releasing

Azo dyes corresponding to the formula (II): ##STR1## wherein G represents a group capable of forming a 5-membered chelate ring and R.sup.5 represents aryl or a thienyl group, combined with metal ions, in particular copper or nickel ions, to form stable azo dye-metal complexes which have advantageous spectral properties. They are therefore particularly suitable for the production of highly light-fast cyan images, e.g. by the Ink-Jet process, in which they may be used directly in the form of colored inks, or by the dye diffusion transfer process, in which they are released image-wise from corresponding dye-releasers in the course of development and transferred to a dye-absorbent layer.

Chelatable 4-thienyl imidazole azo dyes, their use in color photographic

Azo dyes corresponding to the formula (I): ##STR1## wherein R.sup.1 represents a releasable group, R.sup.2 represents H, halogen or sulphonyl, R.sup.3 and R.sup.4 represent H or groups not capable of chelate formation, and Q represents a group for completing a phenyl or naphthyl group, combine with nickel ions to form stable azo dye-metal complexes which have advantageous spectral properties. They are therefore particularly suitable for the production of highly light-fast magenta images, e.g. by the ink jet process, in which they may be used directly in the form of colored inks, or by the dye diffusion transfer process, in which they are released imagewise from suitable dye-releasers in the course of development and transferred to a dye-receptive layer.

Monoazo pyridinol dyes chelated or capable of being chelated with metal

Metal complexes, particularly copper and nickel complexes, of azo dyes corresponding to formula suitable for use as magenta-colored image dyes for the production of colored images by the dye diffusion transfer process. The dyes are linked (in non-metallized form) to a carrier radical provided with a ballast group as so-called color-providing compounds which are associated with a photosensitive silver halide emulsion layer. During development, the metallizable dyes are released imagewise and, after diffusion into an image-receiving layer, are converted into the corresponding metal complexes. ##STR1## In formula II, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent H, F, Cl, Br, --CN, --NO.sub.2, --CF.sub.3, --OCH.sub.3, --SCF.sub.3, alkyl, alkoxy, alkylthio, acylamino, alkyl sulphonyl, aryl sulphonyl, --CO--X or --SO.sub.2 Y; or two adjacent radicals from the group of radicals R.sup.1 to R.sup.4 together represent a fused benzene ring;

Color photographic recording material containing a non-diffusible dye

Process for the preparation of styryl dyestuffs of the formula ##STR1## in which R.sub.1 and R.sub.2 denote hydrogen, alkyl, alkoxy or halogen and

Process for the preparation of styryl dyestuffs

Azo dyes of formula II are released on development from dye releasers which are associated with a light-sensitive silver halide emulsion layer. The azo dyes are chelatable and form with metal ions blue or cyan dye-metal-complex image dyes. ##STR1## In the formula A.sup.1 and A.sup.2 represent electronegative substituents whose meta-sigma values .sigma..sub.m (according to D. H. McDaniel and H. C. Brown in J. Org. Chem. 23, 420 et seq (1958) conform to at least one of the following three relationships:

Color photographic recording material

Cyan images may be prepared by the dye diffusion transfer process, using dye-releasers which on development release diffusible dyes capable of forming light-fast cyan metal-dye-complexes particularly with copper or nickel ions. As also the dye-releasers are capable of complexation, cyan images can be prepared not only from the released dyes but also from the dye-releasers ('retained image'). Released dyes and dye-releasers of the present invention contain a chromophor of the following formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, each represents --H, --F, --Cl, --Br, --CN, --NO.sub.2, --CF.sub.3, --OCF.sub.3, --SCF.sub.3, alkyl, alkoxy, alkylthio, acylamino, alkylsulfonyl, arylsulfonyl, --CO--X or --SO.sub.2 --Y or two adjacent groups R.sup.1 -R.sup.4 together constitute a condensed benzene ring which may contain further substituents;

Photographic recording material with metal complexable, heterocyclic azo

For the production of light-fast yellow images (transfer images and retained images) by the dye diffusion transfer process dye-releasers are useful which on development release diffusible azo dyes which can complex with nickel or copper ions and which in one of their tautomeric forms correspond to the general formula: ##STR1## wherein R.sup.1 represents alkyl, alkenyl or cycloalkyl having up to 8 carbon atoms,

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Leverkusen, Germany

Gerhard Wolfrum