Boehringer Ingelheim Kg

Boehringer Ingelheim Gmbh

Boehringer Ingelheim Zentrale

Gerhard Walther

Karl-Heinz Weber

Claus S Schneider

Franz J Kuhn

Erich Lehr

Adolf Langbein

Herbert Merz

Klaus Stockhaus

Helmut Ensinger

Dieter Hinzen

Albrecht Harreus

Gojko Muacevic

Werner Stransky

Wolfgang Troger

Karin Boke-Kuhn

Jorge Casals-Stenzel

Wolf-Dietrich Bechtel

Wolf D Bechtel

Karl H Weber

Enzio Muller

Gunter Schingnitz

Jorge C Stenzel

Armin Fugner

Ulrike Kufner-Muhl

Karin Boke

Hubert Heuer

Peter Danneberg

Helmut Wick

Wilhelm Frolke

Franz-Josef Kuhn

Kalus Stockhaus

Karl-Heinz Pook

Armin F/u/ Gner

The invention relates to new xanthine derivatives of general formula I, processes for preparing them and their use as pharmaceutical compositions.

Bornyl xanthine derivatives with adenosine-antagonistic activity

The invention relates to new hetrazepines of general formula ##STR1## wherein A, Z, n, X, Y, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the meanings given in the specification.

Hetrazepine compounds which have useful pharmaceutical utility

Xanthines of the formula I ##STR1## wherein R.sub.1 is a C.sub.1 -C.sub.4 alkyl group:

Xanthine derivatives with adenosine-antagonistic activity

The invention relates to new quinuclidines, processes for their preparation and their use as medicaments having cholinomimetic properties.

Quinuclidines, their use as medicaments and processes for their

The invention relates to quinuclidines, processes for their preparation and their use as medicaments having cholinomimetic properties.

The invention relates to new tetrahydropyridine derivatives, processes for preparing them and their use as pharmaceutical compositions with cholinomimetic properties.

Tetrahydropyridine derivatives

The invention relates to new thieno-triazolo-1,4-diazepino-2-carboxylic acid amides of formula I ##STR1## wherein R.sub.1 represents hydrogen, a C.sub.1 -C.sub.4 straight-chained or branched alkyl which can optionally be substituted by halogen, preferably Cl or Br, or by hydroxy, cyclopropyl, C.sub.1 -C.sub.3 alkoxy, preferably methoxy, or halogen, preferably chlorine or bromine;

Methods of using new thieno-triazole-1,4-diazepino-2-carboxylic acid

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms; R.sub.2 is 2-, 3- or 4-pyridyl, phenyl or mono- or di-substituted phenyl, where the substituents are each individually alkoxy of 1 to 2 carbon atoms, fluorine, chlorine, bromine, trifluoromethyl, alkyl or 1 to 4 carbon atoms, hydroxyl or nitro; and

N-heterocyclic substituted -pyrrolidin-2-ones

The invention relates to new 1,4-diazepines of the general formula ##STR1## in which R.sub.1, R.sub.2 R.sub.3, X and A have the meaning indicated in the specification. The new compounds are intended for use for the treatment of pathological states and diseases in which PAF (platelet activating factor) is involved.

Substituted-1,4-diazepines

The invention relates to new thieno-triazolo-1,4-diazepino-2-carboxylic acid amides of formula I ##STR1## wherein R.sub.1 represents hydrogen, a C.sub.1-C.sub.4 straight-chained or branched alkyl which can optionally be substituted by halogen, preferably C1 or Br, or by hydroxy, cyclopropyl, C.sub.1 -C.sub.3 alkoxy, preferably methoxy, or halogen, preferably chlorine or bromine;

Thieno-triazolo-1,4-diazepino-2-carboxylic acid amides

1-(benzyl or pyridylmethyl)-4 or 5-aminomethyl-pyrrolidin-2-ones

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms;

1-benzyl-4- or 5-pyrrolidinomethyl-pyrrolidin-2-ones and nootropic

The invention relates to new thieno-traizolo-1,4-diazepino-2-carboxylic acid amides of formula I ##STR1## wherein R.sub.1 represents hydrogen, a C.sub.1 -C.sub.4 straight-chained or branched alkyl which can optionally be substituted by halogen, preferably Cl or Br, or by hydroxy, cyclopropyl, C.sub.1 -C.sub.3 alkoxy, preferably methoxy, or halogen, preferably chlorine or bromine;

Thieno-traizolo-1,4-diazepino-2-carboxylic acid amides

The invention relates to the use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants.

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Bingen, Germany

Gerhard Walther