Consortium Fur Elektrochemische Industrie Gmbh

Hoechst Aktiengesellschaft

Wacker Chemie Ag

Consortium F&uuml;r Elektrochemische Industrie Gmbh

Wacker Biochem Corporation

Gerhard Schmid

Paul Habermann

Dominique Tripier

Peter Crause

Anton Candussio

Wolfgang Ulmer

August Bock

Mark Harrison

Hans-Jurgen Eberle

Susanne Leonhartsberger

Patrick Polchinski

Pat Polchniski

Günter Wich

The present invention comprises a signal peptide with a cleavage site to a recombinant protein, wherein the last three amino acids before the cleavage site are alanine-phenylalanine-alanine (AFA).

Signal peptide for the production of recombinant proteins

Cyclodextrin inclusion complexes of hydrophobic actives are useful in liquid and solid laundry detergent formulations. The inclusion complexes are stable and capable of releasing their active ingredients gradually during wash and rinse cycles.

Cyclodextrin laundry detergent additive complexes and compositions containing same

A method to stabilize acylglycerols comprising &#x3c9;-3 polyunsaturated fatty acids against oxidative degradation characterized in that &#x3b3;-cyclodextrin is mixed either batchwise or continuously with the acylglycerol comprising &#x3c9;-3 polyunsaturated fatty acids, thus forming a &#x3b3;-CD/acylglycerol complex.

Process for the stabilization of acylglycerols comprising high amounts of &#x3c9;-3 polyunsaturated fatty acids by means of &#x3b3;-cyclodextrin

Secretion of hirudin derivatives

A process for obtaining hirudin derivatives from E. coli secretor mutants which entails:

The invention relates to novel synthetic isohirudins which have improved stability owing to exchange in the region of the Asp-Gly motif. This results, on the one hand, in an increase in the yield during workup and, on the other hand, in making possible pharmaceutical formulation as directly injectable solution ready for use.

Synthetic isohirudins with improved stability

.gamma.-CGTase

Novel synthetic isohirudins with improved stability The invention relates to novel synthetic isohirudins which have improved stability owing to exchange in the region of the Asp-Gly motif. This results, on the one hand, in an increase in the yield during workup and, on the other hand, in making possible pharmaceutical formulation as directly injectable solution ready for use.

The alkalophilic bacteria (DSM 5853) possesses a maltopentaose producing amylase. The maltopentaose producing amylase, and its derivatives modified by gene manipulation, can be expressed in E. coli. These amylases facilitate the production of maltopentaose.

Biologically pure culture of maltopentaose forming amylase producing

A maltopentaose producing amylase, and its derivatives modified by gene manipulation, can be expressed in E. col. These amylases facilitate the production of maltopentaose.

Maltopentaose producing amylases

A process for preparing cyclooctaamylose by enzymatic cleavage of an aqueous preparation of starch in the presence of a complexing agent is disclosed. As a selective complexing agent for cyclooctaamylose, a compound of the formula I is employed. ##STR1## in which A, B, D and E, independently of one another, represent ##STR2## (R=hydrogen, alkyl, hydroxyl, alkoxy or carboxyl radical), and m, n, o and p are within the limits 0 to 20, with the proviso that the number of atoms forming the ring is within the limits from 13 to 24. The compounds prepared by the process of the invention are useful in the medicaments sector, in crop protection and cosmetics, or in the foodstuffs industry.

Growing community of inventors

Munich, Germany

Gerhard Schmid