Gilead Sciences, Inc.

K.u. Leuven Research & Development

Other

Austria Wirtschaftsservice Gesellschaft MIT Beschrankter Haftung

Gerhard Puerstinger

Pürstinger, Gerhard

Gerhard Pürstinger

Johan Neyts

Choung U Kim

David A Oare

Steven S Bondy

Vahid Zia

Eric Dowdy

Erik De Clercq

Heinz-Herbert Fiebig

Johann Hofmann

Gottfried Heinisch

Johnny Easmon

The present invention relates to imidazo[4,5-c]pyridine compounds and pharmaceutical compositions for the treatment or prevention of viral infections, wherein the imidazo[4,5-c]pyridine compounds have the formula: 

Viral inhibitors

The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.

Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment

The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine derivative having the general formula (Z): (formula). The invention also relates to processes for the preparation of compounds according to the invention having above mentioned general formula and their use as a medicine or to treat or prevent viral infections. 

The present invention relates to a pharmaceutical composition for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening ofcompounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections. 

Imidazo 4,5-c pyridine compounds and methods of antiviral treatment

The invention relates to novel 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones that are derived from 2-formylpyridine, 2-acylpyridines, acetyldiazines and acetyl(iso)quinolines. The invention also relates to a novel method for producing 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones and to their use as useful anti-cancer therapeutic agents. The novel compounds are also active against multidrug-resistant cancer cells.

Heterocyclic hydrazones for use as anti-cancer agents

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Innsbruck, Austria

Gerhard Pürstinger