Asta Medica, Aktiengesellschaft

Zentaris Gmbh

Gerhard Nossner

Jurgen Engel

Bernhard Kutscher

Peter Hilgard

Wolfgang Schumacher

Jurij Stekar

Alfred Olbrich

Ulf Niemeyer

Bernd Kutscher

Margrit Stekar

Jurij Stekar, Deceased

A method of treating protozoal and fungal diseases is described, in which an effective amount of a compound of formula I is administered to a host having a protozoal or fungal disease. Also described are methods of treating bone marrow damage composed of administering, to a host having bone marrow damage due to treatment with cytostatic agents or other myelotoxic active ingredients, an effective amount of a compound of formula I

Disease treatment with novel phospholipid derivatives

A process for the preparation of C.sub.14 -C.sub.18 -alkylphosphocholines by reacting an n-alkanol with a chain length of C.sub.14 -C.sub.18 with phosphorus oxychloride in an inert solvent or also without solvent in the presence or absence of a basic substance in a single vessel process and subsequent reaction of the reaction product in an inert solvent with a choline salt in the presence of a basic substance to form phosphoric acid diester chloride, subsequent hydrolysis and isolation of alkylphosphocholine as well as optionally purification using a mixed-bed ion exchanger or in successive steps with an acid ion exchanger and a basic ion exchanger.

Process for the preparation of alkylphosphocholines and the production

Phospholipid derivatives containing higher elements of the Vth main group (P, As, Sb, Bi), their method of preparation and antineoplastic and antimicrobially active medications that can be prepared from the phospholipid derivatives.

Phospholipid derivatives containing higher elements of the fifth main

Phospholipid derivatives containing higher elements of the fifth group

Octadecyl-[2-(N-methylpiperidino)-ethyl]-phosphate and a process for its preparation. This compound is useful for the treatment of cancer.

Octadecyl-[2-(N-methylpiperidino)-ethyl]-phosphate and a process for its

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Offenbach, Germany

Gerhard Nossner