Aventis Pharma Deutschland, Gmbh

Sanofi-A Ventis Deutschland Gmbh

Hoechst Roussel Pharmaceuticals

Gerhard Korb

Hans-Wolfram Flemming

Rudolf Lehnert

Joachim-Heiner Jendralla

Juergen Mueller-Lehar

Andreas Haubrich

Jean-Francois Trotzier

Matthias Braun

Walter Weber

Wolfgang Rybczynski

The present invention relates to a process for the production of squalene and/or sterol in high amounts using an alkaline solution and an organic lysis solvent at high temperature and high pressure for effectively lysing yeast cells and extracting squalene and/or sterol into an organic extraction solvent, thus obtaining squalene and/or sterolin high amount and of high purity.

Production of squalene and/or sterol from cell suspensions of fermented yeast

The invention is directed a process of preparing a compound of formula (I), wherein R1, R2, R3 and z are as defined herein.

Process for carbonylating phenylalkyl derivatives by means of carbon monoxide

The present invention relates to an efficient process for preparing derivatives of 1-(pyridinyl)-1,1-dialkoxy-2-aminoethane of the formula (I), with which compounds of the formula (I) can be prepared in high purity and yield and in the form of the free base without isolating the acetylpyridine oxime of the formula (XI) which is a critical product from a safety point of view as a solid.

Process for preparing pyridine-substituted amino ketal derivatives

A process for obtaining &agr;,&agr;-dimethylphenylacetic acid wherein &agr;,&agr;dimethylbenzyl cyanide is reacted in the presence of sodium hydroxide, water and a C,- and/or C,-alcohol at temperatures above about 100&deg; C. and the &agr;,&agr;-dimethylphenylacetic acid is obtained by acidification.

Process for the preparation of &agr;,&agr;- dimethylphenylacetic acid from &agr;,&agr;-dimethylbenzyl cyanide under normal pressure

A process for the alkylation of compounds of the formula II ##STR1## where the reaction with the alkylating agent is carried out in the presence of a base and a trialkylamine and/or trialkylphosphine.

Process for the alkylation of alkyl-or benzylcyanogen derivatives in the

Process for obtaining 3,7-dialkylxanthines from 3-alkyl-xanthines 3,7-Dialkylxanthines are obtained from the corresponding 3-alkylxanthines using an alkylating agent in the presence of quaternary ammonium and/or phosphonium compounds and, where appropriate, of additional polyethers in a two-phase mixture.

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Hainburg, Germany

Gerhard Korb