Transtissue Technologies Gmbh

Imtec Immundiagnostika Gmbh

Gerd-Rudiger Burmester

Falk Hiepe

Michael Sittinger

Jeannette Marell

Gabriele Riemekasten

Olaf Schultz

Implantable substrate for the healing and/or protection of connecting tissue, preferably cartilage, comprising at least one composition for the activation of locally present cells for tissue regeneration and at least one structure for cell invasion in vivo and/or for the formation of cell matrix and/or for the release of constituents of the employed composition.

Implantable substrates for the healing and protection of connecting tissue, preferably cartilage

Peptides of the antigen Sm-D and their use, in particular for the diagnostics of the SLE. The invention relates to peptides of the antigen Sm-D, comprised of 35 to 45 amino acids, which form a conformation epitope and which are capable of binding autoantibodies, such as they occur in connection with systemic lupus erythematosus (SLE). Particularly preferred is the peptide of 37 amino acids with the structure VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR (SEQ ID NO:3) and its mutants and variants, respectively.

Peptides of the antigen Sm-D and their use, in particular for the

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Berlin, Germany

Gerd-Rudiger Burmester