Boehringer Mannheim Gmbh

Boehringer Ingelheim Zentrale

Aventis Pharmaceuticals Products Inc.

Gerd Assmann

Harald Funke

Christoph Kessler

Rudiger Rueger

Stephan Rust

Horst-Dietrich Helb

Patrice Denefle

Patrick Benoit

Nicolas Duverger

Eric Bruckert

Jean-Charles Fruchart

G&eacute;rald Luc

G&eacute;rard Turpin

The present invention relates to variants of the human apolipoproteine A-I comprising a cystein in position 151, the corresponding nucleic acids and the vectors containing them. It also relates to pharmaceutical compositions comprising said elements and their utilization, particularly in genic therapy.

Variants of apolipoprotein A-I

Method of detecting nucleic acids whose nucleotide sequences differ from one another at a position X. The method uses a set of oligonucleotides where the nucleotides found at position X are complementary to a variant nucleic acids only at this position X. However, with respect to the position of another mismatch Y, the nucleotide sequences thereof differ from one another. The invention further addresses reagents for performing the methods as well as reagents and applications of the method.

Method of detecting variant nucleic acids using extension

Method of detecting variant nucleic acids

A process and apparatus for the distribution and preparation of samples from primary vessels, especially samples of patients' sera, liquid reagents or the like, which are transferred into fixedly mounted secondary vessels of any desired construction, preferably in accordance with the data from a distribution sheet recorded by a control programming apparatus, where the secondary vessels can be moved into position one after the other by means of a transporting carriage for the primary vessel having an associated diluter, this transporting carriage being movable in the x-y plane by means of two stepping motors, and the primary vessel is brought back into its starting position after each delivery or after delivery of the samples intended for the entire series of samples.

Apparatus for distribution and preparation of samples from primary

A process and apparatus for the distribution and preparation of samples from primary vessels, especially samples of patients' sera, liquid reagents or the like, which are transferred into fixedly mounted secondary vessels of any desired construction, preferably in accordance with the data from a distribution sheet recorded by a control programing apparatus, where the secondary vessels can be moved into position one after the other by means of a transporting carriage for the primary vessel having an associated diluter, this transporting carriage being movable in the x-y plane by means of two stepping motors, and the primary vessel is brought back into its starting position after each delivery or after delivery of the samples intended for the entire series of samples.

Process and apparatus for distribution and preparation of samples from

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Munster, Germany

Gerd Assmann