University System of Maryland

Gerardo Vasta

Hafiz Ahmed

Lai-Xi Wang

Anita C Wright

Adam G Marsh

Gargi Bandyopadhyaya

Jos&eacute;to A Fern&aacute;ndez-Robledo

Engin Kaptan

Prasun Guha

Cathleen A Coss

Galectin 3 inhibitors and methods for treating sepsis using the same are provided herein.

Inhibition of galectin 3 binding to the airway epithelial surface to treat or prevent septic shock resulting from influenza and subsequent pneumococcal pneumonia infection

A Thomsen-Friedenreich disaccharide-containing glycopeptide purified from cod fish of approximately 100 kDa (designated TFD) and methods of using the same in the suppression of cancer metastasis is disclosed.

Methods of use for a natural Thomsen-Friedenreich disaccharide compound

A method and assay are described for determining prostate cancer and the general stage of progression of such cancer by quantifying levels of promoter methylation of gal-3, optionally in combination with the quantification of the level of GSTP1 promoter methylation, where the method and assay are non-invasive to a subject and can detect any of Stages I-IV prostate cancer.

Method and assay for determining methylation of GAL3 promoter for early diagnosis of prostate cancer

A method and assay are described for determining prostate cancer and the general stage of progression of such cancer by quantifying levels of expression of different galectin isoforms and/or different levels of promoter methylation of such galectin isoforms.

Method and assay for early diagnosis of prostate cancer

The present invention is directed to oligonucleotides used as amplification primers and assay probes for species-specific detection and identification of the protozoan Perkinsus in shellfish. The oligonucleotides are designed to preferentially hybridize to what has been found to be a species-unique sequence in the target organism's genome. Preferential hybridization means, for example, that the inventive primers amplify the target sequence in,with little or no detectable amplification of target sequences of other species of protozoa such as,thereby making the assay species specific.

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Columbia, MD, United States of America

Gerardo Vasta