Silicon Biosystems S.p.a.

Menarini Silicon Biosystems, Inc.

Gerardo Perozziello

Gianni Medoro

Alex Calanca

Nicolò Manaresi

Giuseppe Giorgini

Giuseppina Simone

Nicolo' Manaresi

Giuseppe Sardella

A sorting chamber () for sorting first particles () from second particles () comprising: an internal chamber (), which is delimited by a base wall (), a top wall (), and a spacer (), set between the base wall () and the top wall (); an internal chamber (), which is at least partially-delimited by the base wall () and top wall (); two passages (), which set in communication the internal chamber () with the external environment; and a plurality of cavities (), which are designed to house the first particles (), are made in the base wall () and have openings () towards the internal chamber () with widths of from 4 to 6 &#x3bc;m.

Sorting chamber for microscale particles

A microfluidic system () for the isolation of cells (C) of at least one given type from a sample; the system () comprises a separation unit (), for transferring at least part of the cells (C) of the given type from a main chamber () to a recovery chamber () in a substantially selective way with respect to further cells (C) of the sample; two valves () are set upstream and downstream of the main chamber (); two valves () are set upstream and downstream of the recovery chamber (); a control assembly () is designed to govern the aforementioned valves (); the system () proposed enables isolation of the cells with a high degree of reproducibility and precision.

Microfluidic device for isolation of cells

A micro-fluidic system comprising a micro-fluidic channel, which has a wall provided with a hole, within which a closing portion of a closing element extends; when the closing portion is arranged within the micro-fluidic channel, the passage of the liquid along the channel is interrupted; by deforming the closing element by suction the closing portion may be lifted and therefore allow the passage of liquid along the micro-fluidic channel.

Micro-fluidic system

A micro-fluidic system comprising a micro-fluidic channel, which has a wall provided with a hole; and a closing element, which is adapted to cooperate with a partition arranged within the micro-fluidic channel in the area of the hole to isolate or connect two segments of the channel; the closing element is made of a photoresist material, in particular a material obtained by the polymerisation of a photopolymerable material.

Growing community of inventors

Bologna, Italy

Gerardo Perozziello