Abbott Laboratories Corporation

Gerard Yvon Paris

Denis G Cimon

Dilbagh Singh Bariana

Anthony Fung

Andre G Pernet

David Lyon Garmaise

Nathan L Shipkowitz

Thomas B Marriott, Iii

Mina D Perlin

Glycerides esterified with one or two moles of valproic acid and optionally esterified with fatty acids at the remaining hydroxy position(s) have been found to have the same useful therapeutic effect as valproic acid alone but without causing gastric irritation.

Glyceryl valproates

Certain 1-substituted-3-loweralkyl-5-(substituted)phenyl-6-aminopyrazolo[3,4-b]pyr azines are provided. They have useful activity as antivirals.

Antiviral pyrazolopyrazines

Specific 4-amino pteridines carrying particular phenyl substituents in the 7-position and no substituents in the 2-position have been found to be excellent nonkaliuretic diuretics at doses of 30 to 500 mg/kg in warm-blooded animals.

Diuretics

Specific 4-hydroxy-pteridines carrying particular phenyl substituents in the 7-position and no substituents in the 2-position have been found to be excellent nonkaliuretic diuretics at doses of 30 to 500 mg/kg in warm-blooded animals.

4-Hydroxy-7-(substituted)phenylpteridines

Triglycerides carrying hydrocarbon acyl moieties in the 1- and 3-positions and the 2-methyl-1,3-benzodioxan-4-on-2-yl moiety in the 2-position exhibit excellent anti-inflammatory properties.

Glycerides with anti-inflammatory properties

Triglycerides carrying the anti-inflammatory drug moiety in the 2-position and hydrocarbon acyl moieties in the 1- and 3-position exhibit excellent anti-inflammatory properties without causing the side effects often associated with the anti-inflammatory drug itself.

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Duvernay, Canada

Gerard Yvon Paris