Feyecon Development & Implementation B.v.

Cooperatie Avebe U.a.

Academisch Ziekenhuis Groningen

Friesland Brands B.v.

Feyecon B.v.

Csm Bakery Solutions Europe Holding B.v.

Bakery Supplies Europe Holding B.v.

Gerard Willem Hofland

Marco Luigi Federico Giuseppin

Albert Thijs Poortinga

Geert Feye Woerlee

Daniela Oana Trambitas

Pieter Sebastiaan Vermeulen

Peter Jan Smits

Wilhelmus G M Agterof

Rajni Bhatia

Erik Peter Bleuel

Maarten Stolk

Wolgang Held

Johannes Hubertus Elise Moonen

Tjerk Jan De Vries

Gerda Maria Van Rosmalen

A method is provided for producing a dehydrated biopolymer powder, said method comprising the successive steps of: a) providing a filter cake comprising biopolymer material and 30 to 60 wt. % of water; b) contacting said filter cake with a pressurized gas to extract water from the filter cake, said pressurized gas having a pressure and a temperature below the critical point of the gas; c) separating water-containing pressurized gas from the dehydrated filter cake; and d) collecting a dehydrated biopolymer powder wherein the pressurized gas has a pressure of at least 0.6 MPa (6 bar) and up to 6 MPa (60 bar), and a temperature of 10 to 40&#xb0; C.

Subcritical gas assisted drying of biopolymer material

The present invention relates to a microencapsulate comprising microcapsules having a diameter of 0.1 &#x3bc;m to 25 &#x3bc;m, said microcapsules comprising: &#x2014;a core particle having a diameter of 90 nm to 23 &#x3bc;m and containing at least 3% of the active component by weight of said core particle; and&#x2014;a coating that fully envelops the core particle and containing at least 20 wt. % of a hydrophobic polymer selected from cellulosic ethers, cellulosic esters, zein, shellac, gluten, polylactide, hydrophobic starch derivatives, polyvinyl acetate polymers, polymers or copolymers derived from an acrylic acid ester and/or a methacrylic acid ester and combinations thereof; wherein the core particle contains a release trigger component and/or the coating contains a release trigger component, said release trigger component being selected from: &#x2014;a water-swellable polymer having a water-uptake capacity at 37&#xb0; C. and pH 7.0 of less than 20 wt. % and a water-uptake capacity at 37&#xb0; C. and pH 2.0 of at least 50 wt. %; and&#x2014;an edible salt having a water solubility at 37&#xb0; C. and a pH of 7.0 of less than 1 mg/ml and a water solubility at 37&#xb0; C. and a pH of 2.0 of at least 5 mg/ml; The microencapsulate of the present invention does not release the encapsulated active component when incorporated in water-containing foodstuffs, beverages, nutritional compositions or pharmaceutical compositions. Following ingestion, however, the active component is released rapidly.

Microencapsulate and process for the manufacture thereof

A process for the preparation of encapsulates, employs: a pumpable emulsion having (i) a continuous phase containing a solvent and a matrix-forming solute dissolved in the solvent and (ii) a dispersed phase; an extractant including supercritical, subcritical or liquefied gas; the solvent being substantially more soluble in the extractant than the matrix-forming solute and the process including the successive steps of: a) combining the pumpable emulsion with the extractant under mixing conditions; b) allowing the formation of particulate encapsulates in which the dispersed phase is encased in a solid matrix of the matrix-forming solute; c) collecting the encapsulates and separating them from the extractant. The present processes is particularly suitable for producing particles containing active ingredients that are very sensitive, whose activity is adversely affected by exposure to oxygen, light, moisture, heat and/or friction.

Process for the preparation of encapsulates through precipitation

The present invention relates to a method of dehydrating pieces of intact plant or animal tissue, said pieces containing at least 30 wt. % of water, the method comprising (i) contacting the pieces of intact tissue with a pressurized gas to reduce the water content of the pieces by at least 50%, said pressurized gas having a pressure of at least 0.5&#xd7;Pand a temperature of at least T&#x2212;60&#xb0; C., Prepresenting the critical pressure of the gas and Trepresenting the critical temperature of the gas, and (ii) separating the pressurized gas from the dehydrated pieces, wherein at least 80 wt. %, preferably at least 90 wt. % of the matter removed by the gas from the pieces of intact plant or animal tissue is water. The invention also provides a method of dehydrating a material containing at least 30 wt. % of water, using a method as described before, followed by drying the separated pressurized gas by contacting said pressurized gas with a water absorbent water adsorbent; and recirculating the dried pressurized gas to the partially dehydrated material.

Dehydration method

The invention relates to the processing of a biological sample for histological analysis. In particular, it relates to a rapid automated processing system that can be operated with continuous throughput and that eliminates the use of toxic solvents such as xylene. Provided is a method for processing a biological sample for histological analysis, comprising contacting the sample with a composition comprising a supercritical or near supercritical fluid followed by impregnating the sample under a pressure of more than 1 bar with an embedding medium, preferably paraffin. Also provided is a processor () for preparing at least one sample () for histological analysis, comprising at least one process reactor () for the at least one sample (), characterized in that the processor () comprises supplying means () for supplying to the reactor () at least one substance of which at least one is in supercritical phase or near supercritical phase and at least one supplying means () for adding the embedding medium to the reactor () through conduit ().

Method for histoprocessing

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Hoogmade, Netherlands

Gerard Willem Hofland