Emd Millipore Corporation

Merck Patent Gmbh

Millipore Corporation

Gerard Muller

Stephane Olivier

Mathieu Arrault

Stéphane Jean Marie Olivier

Jerome Geyer

Christian Schann

Christian Clauss

Frédéric Reynes

Jean-Jacques Richert

Jeffrey S Busnach

Jeffery S Busnach

Julien Boeuf

A sample preparation container, preferably for use in sterility testing, comprising a housing () having a housing wall () defining an inside space (), a support on which a membrane filter is placed or is to be placed so as to get in contact with a sampling fluid to be introduced into the inside space (), and at least one inlet opening () to the inside space () and at least one outlet opening from the inside space (). A sampling port () is provided for allowing access from the outside to the inside space (), wherein said sampling port () is closed by a septum () and the septum () is separated from the inside space () by a barrier wall () which is preferably piercable or breakable on application of an external force, preferably applied through a sampling instrument like a needle ().

Sample preparation container

A dispenser for opening a tape like packaging comprising first and second films releasably connected to each other, forming envelopes sealed around an object, and disposed sequentially with a predetermined pitch. The dispenser comprises a space for holding a container of the packaging, a separator through which the packaging can be passed, for spreading apart and separating the films at an outlet thereof when a pulling force is acting on said first and second films, thereby opening envelopes and releasing the objects contained therein, and means for winding up separated first and second films of the tape like packaging. The separator further comprises a cover member that is articulated to the dispenser to be movable between a closed position and an open position.

Dispenser for opening a tape-like packaging

A take-off needle comprises a hollow lance having a distal end adapted to perform a insertion operation, said hollow lance being connected to at least one pipe provided with a spigot for it to be connected to a tube, and comprising a body for holding the hollow lance and pipe relative to each other such that the spigot projects from the holding body, said needle timber comprising two flanges held on respective sides of and spaced from the holding body by virtue of a spacer disposed between each flange and the holding body, said flanges extending in a longitudinal direction from the spigot to the vicinity of the proximal end of the hollow lance, the width of each flange being greater than the width of the portion of the holding body facing the flanges.

Holding needle comprising gripping cheeks

A take-off needle comprises a hollow lance having a distal end adapted to perform a insertion operation, said hollow lance being connected to at least one pipe provided with a spigot for it to be connected to a tube, and comprising a body for holding the hollow lance and pipe relative to each other such that the spigot projects from the holding body, said needle further comprising two flanges held on respective sides of and spaced from the holding body by virtue of a spacer disposed between each flange and the holding body, said flanges extending in a longitudinal direction from the spigot to the vicinity of the proximal end of the hollow lance, the width of each flange being greater than the width of the portion of the holding body facing the flanges.

The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like. A variety of inserts may be used in the same plate to create a minilab on a plate that is capable of conducting several steps of a process on the same (e.g (e.g. filter, wash, bind, elute, label, etc).

Universal filter plate

Universal filtration plate

The method includes the step of positioning the device on a sheath () having, for each latching tab (), a portion adapted to be housed between this tab and a cylindrical wall of the device; the step of making the sheath enter between each tab and the cylindrical wall until means preventing the withdrawal of the tabs are released; and the step of moving the two bodies () away from each other. The instrument has, in addition to the sheath (), a guidance slide ().

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Urmatt, France

Gerard Muller