Becton Dickinson and Company Limited

Gerard Lotz

Dwight Livingston

Ammon David Lentz

Michael A Brasch

Timothy M Wiles

Ming-Hsiung Yeh

Brent Ronald Pohl

Charles C Yu

Kevin Bailey

Patrick Shawn Beaty

Ming-hsiung Yeh

Mei Yang-Woytowitz

Liping Feng

Ben Turng

Gary F Hershner

Eric Ursprung

Xiaofei Chang

Patrick R Murray

An apparatus and associated methods of use for a controlled combination of reagents is disclosed. The apparatus includes a vessel, a vessel insert, and a cap element. The vesselhas a body portionfor receiving a biological sample. The vessel insertreceives at least one reagent therein. Preferably, the vessel insertis received in a portionof the vessel. The cap elementis attached to the vesselto secure the vessel insertin the vessel. During use, the vessel insertis adapted to release its contents when the biological sample is introduced into the body portionof the vesselupon application of an intermixing force to the vessel insert. A variety of intermixing forces may be applied, depending upon the embodiment of the present invention and its associated methods of use.

Blood culture bottles with mechanisms for controlled release of substances into culture media

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Fallston, MD, United States of America

Gerard Lotz