Institute for Medical Research

Coriell Institute for Medical Research

Gerard J McGarrity

Dennis A Carson

Gary H Butler

Hitoshi Kotani

A highly purified arginine deiminase is obtained using a two-step purification procedure. The arginine deiminase is isolated and purified from various species of mycoplasmas and is resistant to proteinase K. The growth of tumor cells can be inhibited by administering proteinase K-resistant arginine deiminase or a PEG-conjugate thereof.

Protease K resistant arginine deiminase, its method of preparation and

A clinical diagnostic method capable of rapidly detecting the presence of Mycoplasma pneumoniae in infected humans is taught. The method allows a proper course of therapy to be chosen within one day of presentation of the patient.

Rapid detection of mycoplasmas

Detection of mycoplasma infection in an animal cell culture is accomplished by growing animal cells from a culture in a growth medium in the presence of 6-methylpurine deoxyriboside and determining whether animal cells are killed.

Growing community of inventors

Wenonah, NJ, United States of America

Gerard J McGarrity