Abbott Molecular Inc.

Abbott Laboratories Corporation

Ibis Biosciences, Inc.

Gerard J Gundling

Mark W Eshoo

Edward N Granados

Dae Hyun Kim

Scott G Safar

Herbert A Marble

Natalie A Solomon

Wai-Bing X Mak

Ronald E Kukla

Dae Hyun H Kim

Lendell Cummins

Thomas Laffler

Magdalena Szostak

Cristina A Ivy

Robert Kowal

The present disclosure relates to systems and methods for purifying nucleic acid. In particular, the present disclosure relates to systems and methods for purifying nucleic acids using metal or metal oxide compositions.

Purification of nucleic acids using titanium oxides

Purification of nucleic acids using copper-titanium oxides

The present disclosure relates to systems and methods for nucleic acid isolation. In particular, the present disclosure provides systems and methods for isolating low molecular weight circulating nucleic acids from bodily fluids (e.g., plasma).

Systems and methods for isolating nucleic acids

Provided herein is technology related to processing samples of nucleic acids and particularly, but not exclusively, to methods for enriching samples for small nucleic acids, such as small circulating cell-free DNA.

Enrichment of small nucleic acids

Purification of nucleic acids using metal-titanium oxides

Compositions and techniques for the extraction, enrichment and isolation of nucleic acids from yeast in a whole blood sample using amine monomers are disclosed herein.

Compositions and methods for nucleic acid extraction

The invention provides methods for extraction of fungal (e.g., yeast spp., filamentous fungal spp.) nucleic acid (e.g., DNA, RNA) from a sample (e.g., be human or veterinary clinical or research samples, agricultural samples, agricultural commodity samples, food products, or environmental samples). In some embodiments, the present invention provides enhanced nucleic acid extraction from samples comprising fungal cell(s) wherein enzymatic (e.g., lysostaphin treatment, lyticase treatment) sample treatment is performed in combination with mechanical (e.g., bead beating) sample treatment.

Fungal nucleic acid extraction

Compositions and techniques for the extraction, enrichment and isolation of nucleic acids from cellular source material using an ammonium hydroxide-based solution are disclosed herein.

The present invention is a new and non-obvious method for the improved and simplified purification of nucleic acids.

One-step procedure for the purification of nucleic acids

Compositions and techniques for the extraction, enrichment and isolation of nucleic acids from fresh, fixed or fixed and embedded cells, tissues, biological materials and cellular source material using amine monomers are disclosed herein.

Growing community of inventors

Des Plaines, IL, United States of America

Gerard J Gundling