Janssen Pharmaceutica Nv

Gerard Frans Cauwenbergh

Marc Joris De Brabander

The use of a compound having the formula ##STR1## wherein R represents methyl or ethyl, for regulating the greasiness of the skin, particular novel physical forms of said compound, cosmetic compositions comprising said agent, processes for preparing said agent and compositions, and a method of reducing the greasiness of the skin.

Agent for regulating the greasiness of the skin

Agents for preserving or restoring the soundness of the skin by administering a serotonin antagonist which in particular is a compound of formula ##STR1## a salt or a stereoisomeric forms thereof; wherein Q is ##STR2## and R.sup.1 is --X--Ar (c), ##STR3## the agent of formula (I) preferably being ketanserin.

Agents for preserving or restoring the soundness of the skin

Agent for use as an anti-irritant

A method of topically treating subjects suffering from acne, hyperkeratotic dermatoses and photo-aging of the skin, by administering to the skin of said subjects an effective amount of the antifungal compound ketoconazole and a retinoid is disclosed. Compositions comprising an inert carrier and as active ingredients the compound ketoconazole and a retinoid are described.

Growing community of inventors

Vorselaar, Belgium

Gerard Frans Cauwenbergh