University of California

Other

University of Colorado

Gerard Boss

Michael W Berns

Matthew D Brenner

Sari Mahon

Adriano Chan

Vikhyat Bebarta

Ryan M Spitler

Hema Rangaswami

Darren Casteel

Renate Pilz

Compositions and methods for treatment of aortic disease in a subject in need comprising an effective amount of cobinamide. Aortic diseases include for example aortic aneurysm, aortic dissection, or aortic dilation. Aortic disease can be caused for example by Marfan syndrome or oxidative stress.

Treatment for aortic aneurysms

Methods and compositions for treating cyanide, sulfide, or methane-thiol exposure in a subject. The compositions may include one or more cobinamide compounds, such as an amino-tetrazole-cobinamide and/or a di-(amino-tetrazole)-cobinamide.

Cobinamide compounds as a cyanide, sulfide, or methane-thiol antidote

The invention generally relates to methods for treating and/or reducing the severity of a wound in a subject. Provided are wound therapies combining low level light therapy (LLLT) and a nitric oxide (NO) donor to treat and/or reduce the severity of the wound. The LLLT and NO donor may be administered concurrently or sequentially. Also provided are wound treatment systems and kits including a light source and a NO donor, which are administered to a wounded subject. Further provided are pharmaceutical compositions that comprise a NO donor and are formulated to be administered in conjunction with LLLT.

Methods and systems of treating wounds

Growing community of inventors

La Jolla, CA, United States of America

Gerard Boss