Vicam L.p.

Massachusetts Institute of Technology

Boston University

Gerald N Wogan

Steven R Tannenbaum

Thomas L Benjamin

Thomsen J Hansen

David M Livingston

Barbara Jackson

Joan Chen-Wu

John D Groopman

Frederick G Bargoot

Franz Fiedler

Christopher Ferrari

Calvert L Green

An assay method is provided to easily and quickly detect the presence of organisms capable of being cultured, such as bacteria, characterized by antibody capture of the organism of interest by use of specialized magnetic beads, incubation of the captured cells to form colonies; removal of material from the colonies with a colony lift membrane; and detection of the colony material on the membrane sheet by use of labeled antibodies, PCR or nucleic acid probes.

Assay method for detecting presence of bacteria

Assay method for detecting the presence of bacteria

An assay method is provided to quickly detect the presence of Listeria strains in samples, characterized by the use of antibodies to selectively capture the peptidoglycan and teichoic acid components of the listeriae bacterial cell wall.

Assay method for detecting listeria

An affinity matrix and a method for the detection of low molecular weight compositions such as aflatoxins are provided utilizing specific monoclonal IgM antibody having an affinity constant not less than about 1.times.10.sup.9 liters per mole. Methods for the preparation and use of such affinity matrices are also given. The detection is rapid, accurate, reproducible, and allows for quantitative recovery of the composition of interest.

Affinity column and process for detection of low molecular weight toxic

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Belmont, MA, United States of America

Gerald N Wogan