Atrix Laboratories, Inc.

Gerald L Yewey

Richard L Dunn

Arthur J Tipton

Michael L Radomsky

Nancy L Krinick

Gerbrand Brouwer

Jeffrey L Southard

John E Urheim

Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The controlled release component includes an active agent. These compositions may be introduced into the body of a subject in liquid form which then solidify or cure in situ to form a controlled release implant or a film dressing. The liquid delivery compositions may also be employed ex situ to produce a controlled release implant. Methods of forming a controlled release implant and employing the liquid formulations in the treatment of a subject are also provided.

Liquid delivery compositions

A medical device which is a surgically implantable device coated with an adjunctive polymer system. The adjunctive polymer system forms a solid matrix when introduced into a human or animal body. The adjunctive polymer system can contain a drug or a medicament which is released over time from the solid matrix. The adjunctive polymer system contacts body tissue into which the surgically implantable device is implanted.

Adjunctive polymer system for use with medical device

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Fort Collins, CO, United States of America

Gerald L Yewey