Centaur, Inc.

University of Kansas

Gerald Henry Lushington

Luis Tonatiuh Melgarejo Garcia

Annika Linde

Jeffrey Aube

Frank John Schoenen

Roy A Jensen

Lisa M Harlan-Williams

Luis Tonatiuh Garcia

The present disclosure relates to antimicrobial agents and methods of using such agents. The disclosure includes antimicrobial agents having broad spectrum antimicrobial activity, nucleic acids and amino acid sequences encoding such antimicrobial agents, as well as methods of using the antimicrobial agents. The antimicrobial agents of the disclosure may be used to reduce survival of a microbe, as an antimicrobial therapeutic, in microbial treatment protocols, and in research, as well as other uses related to reducing microbe survival. In addition, the disclosure also includes compositions, as well as articles of manufacture, that comprise a broad spectrum antimicrobial agent.

Water buffalo derived dimeric peptide containing proline for antibiotic therapies

Water buffalo derived peptide antibiotic therapies

Water buffalo derived monomeric peptides containing proline for antibiotic therapies

A pharmaceutical composition for use in treating, inhibiting, and/or preventing breast and/or ovarian cancer can include: a molecule having a structure of one of Compounds 1-38, pharmaceutically acceptable salt thereof, or analog thereof; and a pharmaceutically acceptable carrier containing the compound. The pharmaceutically acceptable carrier can be configured for oral, systemic, transdermal, intranasal, suppository, parenteral, intramuscular, intravenous, or subcutaneous administration. The compound can be present in the composition in a therapeutically effective amount for treating, inhibiting, and/or preventing breast and/or ovarian cancer. Also, the compound can be present in a therapeutically effective amount for enhancing production of BRCA1.

BRCA1-based breast or ovarian cancer treatment agents and methods of use

Growing community of inventors

Lawrence, KS, United States of America

Gerald Henry Lushington