Ethicon, Gmbh

Kardium Inc.

Kodak Graphic Communications Canada Company

Angiotech Pharmaceuticals, Inc.

Gerald Floyd Cummings

Alexei Goraltchouk

Lev Drubetsky

Alexander Naimagon

Robert A Herrmann

Shane Fredrick Miller-Tait

David Craig Wilson

Michael Scott Bogelund

Pulsed field ablation systems are disclosed, some of which may include an output pulse generation circuit and a high voltage pulse generation circuit electrically connected to the output pulse generation circuit. The high voltage pulse generation circuit may be configured to deliver a high voltage pulse set to the output pulse generation circuit. The output pulse generation circuit may be configured to generate an output pulse set at least in response to the high voltage pulse set. The output pulse set may be deliverable to a set of selectable electrodes and may be configured to cause pulsed field ablation of tissue. Each pulse in the output pulse set may have a rise time that is shorter than a rise time of at least one high voltage pulse in the high voltage pulse set.

Systems and methods for treating tissue with pulsed field ablation

A self-retaining suture comprises a composite filament. The filament has retainers on the surface such that the filament can engage and retain tissue without knots. The filament comprises at least two materials having different properties. A surface material of the filament has properties which enhance the formation, elevation and/or deployment of the retainers. A core material of the filament has properties which enhance the tensile strength of the filament. The surgical filament is thin and flexible and may be used for suturing. Methods for manufacturing the filament and retainers are also described.

Composite self-retaining sutures and method

Provided herein are sutures to be used in a procedure applied to tissue, and methods for forming such sutures. A suture can include an elongated suture body having a periphery, and a plurality of retainers formed from molten material applied to portions of the periphery. The retainers can extend from and be arranged along at least a segment of the elongated suture body. The retainers can be formed by applying molten material to portions of the periphery of the elongated suture body and cooling the material to form the retainers.

Self-retaining sutures with retainers formed from molten material

Provided herein are sutures for use in a procedure applied to tissue, and methods for forming such sutures. Some sutures include bi-directional retainers, each of which can be deployed in two directions, but once deployed in one direction, resist motion in the opposite direction. Other sutures include uni-directional retainers that are conical in shape, and include tissue engaging protrusions that extend from edges and/or angled walls of the conical retainers.

Self-retaining sutures with bi-directional retainers or uni-directional retainers

Provided herein are sutures to be used in a procedure applied to tissue, and methods for forming such sutures. A suture can include an elongated suture body and a plurality of heat-contact mediated retainers extending from and along the elongated suture body. The heat-contact mediated retainers can be formed by temporarily contacting the elongated suture body with one or more heated element.

Self-retaining sutures with heat-contact mediated retainers

A self-retaining suture comprises a variable-dimension filament which varies in size and/or shape along the length of the filament. The variation in size and/or shape results in a variation in the distribution of filament material from one region of the filament to the next. The filament has retainers formed in the surface such that the filament can engage and retain tissue. The retainers are formed in a manner that makes use of regions of the filament where additional material is distributed. The resulting self-retaining suture has a greater minimum cross-section than would be created using an equivalent uniform filament. The resulting self-retaining suture consequently has a greater tensile strength. Methods for manufacturing the filament and retainers are also described.

Self-retaining suture with variable dimension filament and method

In embodiments of the invention, a manufacturing process produces and an. Article produced has a self-retaining suture wherein a force is used to squeeze the suture causing retainers to form out of material from the suture body. In an embodiment of the invention, fins are formed between the retainers and the suture body, wherein said fins support the retainers. In another embodiment, retainer stops are provided in order to prevent the retainer from settling back in the body of the suture.

Self-retainers with supporting structures on a suture

In a drum based imaging system where it may be necessary to change the drum to accommodate different imaging media sizes there is a need to adapt the drum rotational drive system to control the new drum load. An automated process for updating the control parameters without requiring user intervention uses parameter identification or adaptive control to identify or characterize the new drum load.

Growing community of inventors

Port Moody, Canada

Gerald Floyd Cummings