Galvani Bioelectronics Limited

Ucl Business Plc

Gerald Edwin Hunsberger

Daniel John Chew

Matteo Donega

Arun Sridhar

Morten Hansen

Rizwan Bashirullah

David Holder

Sebastien Ouchouche

Cindy Au

Kirill Aristovich

Eric Irwin

Refet Firat Yazicioglu

Faisal Zaidi

Robert W Coatney

Pey-Jiun Ko

David Karl Lee Peterson

Paul Matteucci

A system for stimulation of a nerve and measuring impedance. The system includes a neural interface device including a plurality of electrodes; a voltage or current source operatively connected to at least a subset of the electrodes, wherein the voltage or current source is configured to generate an electrical signal to be applied to the electrodes; an impedance measuring module operatively connected to at least a subset of the electrodes, wherein the impedance measurement module is configured to measure the impedance between the electrodes; and a controller arranged to determine an amplitude of an action potential induced in the nerve, via the electrical signal, based on the measured impedance and to adjust the electrical signal in order to induce an action potential having a target amplitude.

Neural interface device for stimulation of a nerve and measuring impedance

A nerve interface device including at least one cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the at least one cuff portion, each ring of electrodes including a plurality of electrodes. Each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The plurality of pairs of electrodes includes at least a first pair of electrodes, the first pair of electrodes mounted on the at least one cuff portion. The at least one cuff portion includes an asymmetric configuration about a central axis perpendicular to the longitudinal cuff axis.

Nerve stimulation device for unidirectional stimulation and current steering

There is provided a neural interface device for unidirectional stimulation of a nerve including at least one A-type nerve fiber or at least one at least partially myelinated nerve fiber. The device includes an electrode arrangement for placing on or around the nerve. The electrode arrangement includes a first electrode configured to be positively charged and a second electrode configured to be negatively charged, where the surface area of the second electrode is larger than the surface area of first electrode.

Bipolar and tripolar confirguration for unidirectional stimulation of A-type nerve fibers

Modulation of neural activity of a ganglion, by applying a signal to a sympathetic nerve adjacent to the ganglion, results in preferential reduction of sympathetic signals to an effector, thereby providing ways of treating and preventing conditions associated with exacerbated sympatho-excitation.

Neuromodulation of ganglia

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Brentford, United Kingdom

Gerald Edwin Hunsberger