Janssen Pharmaceutica Nv

Janssen Pharmacetuica N.v.

Georges H Van Daele, Deceased

Jean-Paul R Bosmans

Joannes Adrianus Schuurkes

Frans M Van Den Keybus

Peter Jules Van Daele, Heir

Glenn Kurt Van Daele, Heir

Marie L Hendrickx, Heiress

Kurt Godfried Van Daele, Heir

Peter Jv Van Daele, Heir

Marie-Louise Hendrickx, Heir

Glenn Kl Van Daele, Heir

Kurt Gce Van Daele, Heir

The present invention is concerned with a novel benzamide derivative for formula (I). ##STR1## Pharmaceutical compositions comprising said novel compounds, processes for preparing compounds and compositions, and the use thereof as a medicine, in particular in the treatment of conditions involving a decreased motility of the intestine are described.

Enterokinetic benzamide

N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives, their N-oxide forms and pharmaceutically acceptable salts having gastrointestinal motility stimulating properties, compositions containing these compounds as active ingredient and methods of treating warm-blooded animals suffering from the decreased peristalsis of the gastrointestinal system.

N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2h-benzopyran,

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Turnhout, Belgium

Georges H Van Daele, Deceased