Eli Lilly and Company

Other

The Quaker Oats Company

Elan Pharmaceuticals, Inc.

Athena Neurosciences, Inc.

George W Huffman

James E Audia

Lee H Latimer

Warren Jaye Porter

Thomas Charles Britton

Eugene D Thorsett

Jeffrey S Nissen

Jay S Tung

Jon Kevin Reel

Thomas Edward Mabry

James Joseph Droste

Jing Wu

Beverly K Folmer

Varghese John

William Leonard Scott

Clark Norman Eid

Richard Craig Thompson

Stephen Charles Wilkie

Denis W Akerberg

Carl A Rude

David Elmer Vietti

John Varghese

Joseph P Wuskell

William J Pentz

Disclosed are compounds which inhibit &#x3b2;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &#x3b2;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Methods and compounds for inhibiting &#x3b2;-amyloid peptide release and/or its synthesis

Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds

Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis.

Compounds for inhibiting &bgr;-amyloid peptide release and/or its synthesis

Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Methods and compounds for inhibiting &bgr;-amyloid peptide release and/or its synthesis

The new composition of matter, 2,2'-isopropylidine bis(tetrahydrofuran) and method of preparation.

2,2'-Isopropylidine bis(tetrahydrofuran)

3-Benzothienylglycines are prepared by reaction of a benzothiophene with an .alpha.-hydroxyglycine derivative in the presence of trifluoroacetic acid.

Preparation of 3-benzothienylglycines

A method and composition for forming a dry free-flowing particulate solid is disclosed which utilizes a novel binder system for bonding particles of carbon, sand and/or other solid particulate materials. The solid, non-sticky binder system comprises furfural, solid resin, (such as a phenolic resin), which is not sticky at room temperature and is soluble in furfural, and a liquid amine having free hydrogens on the amine nitrogen which amine is capable of reacting with furfural. This system is capable of adhering to such particles while retaining the free-flowing characteristics of the particles. The free-flowing particulate solid thus formed may be shaped, extruded or compression molded as necessary to form the desired article. A shaped mass of this particulate material is converted to an integral mass by warming or compressing. While the binder is curable at room temperature over a long period of time, the cure rate may be accelerated by increases in temperature. Carbonization of the resin system yields a high carbon residue.

Method and composition for a furan-modified phenolic novolak binder

Certain halogenated phenylthioacetamido cephalosporanic acids and derivatives thereof, e.g., 7-[2'-(2',5'-dichlorophenylthio)acetamido]cephalosporanic acid, are effective antibiotics against Staphylococcus aureus cultures which show heterogeneous resistance to methicillin.

Method for treating methicillin resistant staphylococcus aureus

Method for treating methicillin resistant Staphylococcus aureus

Halogenated phenylthioacetamido cephalosporins

Growing community of inventors

Carmel, IN, United States of America

George W Huffman