Syngenta Corporation

Syngenta Participations Ag

Syngenta Crop Protection Ag

George Robert Hodges

Alan James Robinson

Lisa Mitchell

Martin Charles Bowden

David Anthony Jackson

Dominik Faber

Alexandre Christian Saint-Dizier

Andrew Charles Shaw

The present invention relates to methods of initiating a reaction represented by scheme 1 wherein Q is optionally substituted aryl or optionally substituted heteroaryl; X is halogen or a sulphonate; P is an organic radical; R is hydrogen or an organic radical; wherein the catalyst comprises copper and a ligand; comprising providing the compound of formula III in liquid form prior to contacting the compound of formula III with the catalyst.

Methods for the preparation of aryl amides

The invention relates to a process for the preparation of formula (I) which process comprises pyrolyzing a compound of formula (II) wherein X is chloro or bromo, and to compounds which may be used as intermediates for the manufacture of the compound of formula I and to the preparation of said intermediates. 

Process for the preparation of dichlorofulvene

The present invention relates to methods of initiating a reaction represented by scheme (1), wherein Q is optionally substituted aryl or optionally substituted heteroaryl; X is halogen or a sulphonate; P is an organic radical; R is hydrogen or an organic radical; wherein the catalyst comprises copper and a ligand; comprising providing the compound of formula III in liquid form prior to contacting the compound of formula III with the catalyst. 

The invention relates to a process for the preparation of fungicidally active compounds such as tricyclic amine derivatives (I). The process involves coupling of a carboxylic 5 acid e.g. a compound of formula (II) with an aniline, e.g. a compound of formula (III) in the presence of a boronic acid catalystor an antimony catalyst (II)(III)(I) wherein R1, R2, R3, R4, R5, R6, R7, X, Y and Het are defined in the specification. 

Growing community of inventors

Bracknell, United Kingdom

George Robert Hodges