Adria Laboratories Inc.

Rhone-poulenc Rorer Pharmaceuticals Inc.

Rorer Pharmaceutical Corporation

George R Felt

Sudhakar S Wagle

Herbert W Borleis

Donna K Multhauf

An aerosol spray dispenser of flowable pharmaceutical product is provided with a flotation stabilizing arrangement such that it will float in water in a stabilized erect position even when empty of product; a scale is associated with the dispenser so that the depth at which it floats can be read by comparing the position of the surface of the water in which it floats with graduations on the scale. The stabilizing action may be obtained by placing the dispenser in a floatable bottom-weighted vial, with the scale located in the exterior of the vial, and the combination of vial and dispenser then floated in water. In other embodiments the vial need not be used, in which case the dispenser itself may be bottom-weighted to assure its stabilized erect flotation and the scale placed on the exterior of the dispenser; or, a cap may be provided for the dispenser which is positioned on the dispenser while both are floated in the water, the cap being top-weighted so that the assembly floats stably upside-down. In the latter case the graduations may be placed on the dispenser, or on a strip integral with the cap extending along the outside of the dispenser; alternatively, the cap may be provided with an integral skirt which extends completely around the dispenser and to its bottom end, with the scale located on the exterior of the skirt.

Product-dispensing method and apparatus

A bandage for the continuous administration of nitroglycerin to the skin comprising a backing member defining one exterior surface, an internal backing layer with calibrations thereon for accurate measurement of the amount of nitroglycerin ointment to be deposited thereon, an adhesive layer surrounding the internal backing layer for attachment to the skin, and a releasable backing member applied to the adhesive layer.

Bandage for the topical administration of controlled amounts of

Dose measuring medicinal applicator

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Brown Deer, WI, United States of America

George R Felt