Abbott Laboratories Corporation

University of California

Other

George J Dawson

Suresh M Desai

Anthony Scott Muerhoff

Thomas P Leary

Isa K Mushahwar

Tami J Pilot-Matias

John N Simons

Robin A Gutierrez

James Carl Erker

Larry G Birkenmeyer

James L Stewart

George G Schlauder

Sheri L Buijk

Dinesh O Shah

A Scott Muerhoff

Bruce J Dille

Charles Chiu

Kevin Y Cheng

Matthew Frankel

Kenn Forberg

Deanna Lee

Michael Berg

Kelly Coller

Sushil G Devare

James M Casey

John C Prostko

Richard R Lesniewski

Stephen H Dailey

John R Hackett, Jr

Kevin R Rupprecht

Ruthie E Coffey

Lily Jiang

Dominique P Bridon

John R Hackett

Christopher C Marohnic

Robert J Carrick

M Felicia Bogdan

Mark F Knigge

Keeve D Jaffe

Michelle Chalmers

Adrienne L Gilbert

Teresa K Surowy

Sarah L Kidd

Pamella A Schroeder-Poliak

Yu Cheng

Xingli Jiang

Robin A Guetierrez

Furesh M Desai

John Hackett

John Prostko

Provided herein are compositions, methods, and kits for detecting human2 (HPgV-2). In certain embodiments, provided herein are HPgV-2 specific nucleic acid probes and primers, and methods for detecting HPgV-2 nucleic acid. In other embodiments, provided herein are HPgV-2 immunogenic composition compositions, methods of treating a subject with immunogenic HPgV-2 peptides, and methods of detecting HPgV-2 subject antibodies in a sample.

Compositions and methods for detecting human pegivirus 2 (HPgV-2)

Provided herein are compositions, methods, and kits for detecting human Pegivirus 2 (HPgV-2). In certain embodiments, provided herein are HPgV-2 specific nucleic acid probes and primers, and methods for detecting HPgV-2 nucleic acid. In other embodiments, provided herein are HPgV-2 immunogenic composition compositions, methods of treating a subject with immunogenic HPgV-2 peptides, and methods of detecting HPgV-2 subject antibodies in a sample.

The present invention generally relates to combination immunoassays, reagents and kits for simultaneous detection of HCV antigens and anti-HCV antibodies in a test sample.

HCV antigen-antibody combination assay and methods and compositions for use therein

Compositions and methods for detecting human Pegivirus 2 (HPgV-2)

A polypeptide comprising the contiguous amino acids 1-198 of SEQ ID NO: 2; a polypeptide, which comprises a contiguous amino acid sequence that is at least about 95% identical to the contiguous amino acids 1-198 of SEQ ID NO: 2, an epitope that is immunoreactive with an antibody that specifically binds to the core protein of hepatitis C virus (HCV), and an epitope that is immunoreactive with an antibody that specifically binds to the NS4 region of HCV; a nucleic acid encoding such a polypeptide; a host cell comprising such a nucleic acid; an immunodiagnostic reagent comprising such a polypeptide; a kit comprising such an immunodiagnostic reagent; and a method of determining the presence, amount, or concentration of anti-HCV antibodies in a test sample.

Materials and methods for assay of anti-hepatitis C virus (HCV) antibodies

The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of, and methods of using these polynucleotides and polypeptides in the detection ofantibodies or anti-antibodies in a subject. The invention finds particular useful application in identifying recent exposure to

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The present invention relates to one or more peptides which may be used to test for the presence of antibodies to. These peptide are selected based on the strength and specificity of the human antibody response to. These peptides alone or in combination have a variety of uses, for example, as a component of a diagnostic assay or kit.

The subject invention relates to nucleic acid sequences and amino acid sequences encoded thereby, derived from the Merozoite Surface Protein (MSP1) gene of thespeciesand. Such genes and proteins have many beneficial diagnostic as well as therapeutic uses.

The subject invention relates to nucleic acid sequences and amino acid sequences encoded thereby, derived from the Merozoite Surface Protein (MSP1) gene of thespeciesandSuch genes and proteins have many beneficial diagnostic as well as therapeutic uses.

The subject invention relates to methods for the simultaneous detection of Hepatitis C Virus (HCV) antigens as well as antibodies produced in response to HCV antigens. Furthermore, the subject invention allows one to detect antigens in the early, acute stage of infection, even prior to the development of antibodies, thereby allowing for early detection of infected blood and blood products, thus improving the safety of the blood supply.

Methods for the simultaneous detection of HCV antigens and HCV antibodies

Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.

Non-a, non-b, non-c, non-c, non-d, non-e hepatitis reagents and methods for their use

Growing community of inventors

Libertyville, IL, United States of America

George J Dawson