Northern Illinois University

Loma Linda University

Fermi Research Alliance, LLC

University of Wollongong

George Coutrakon

Nicholas Karonis

Kirk Duffin

Scott N Penfold

Vishnu Zutshi

Bela Erdelyi

Kevin Naglich

Paul Rubinov

Victor Rykalin

Michael F Moyers

Daniel W Miller

Jon W Slater

Jeffrey V Siebers

David B Legg

A proton computed tomography (pCT) detector system, including two tracking detectors in sequence on a first side of an object to be imaged, two tracking detectors in sequence on an opposite side of the object to be imaged, a calorimeter, and a computer cluster, wherein the tracking detectors include plastic scintillation fibers. All fibers in the detector system are read out by Silicon Photomultipliers (SiPM). A method of imaging an object by emitting protons from a source through two tracking detectors, through and around the object, and through two opposite tracking detectors, detecting energy of the protons with a calorimeter, and imaging the object.

High performance computing for three dimensional proton computed tomography (HPC-pCT)

High performance computing for three dimensional proton computed tomography (HPC-PCT)

The present invention is directed to a method for radiation beam therapy delivery system normalization and dose calibration. A prescribed treatment plan is compared to a database of pre-existing and pre-calibrated treatment plans. Upon existence of a matching plan, appropriate calibration factors are assigned to the delivery system monitors according to the pre-existing plan. Variations in delivery system operation are corrected by independent correction of all delivery system monitors established by standard relative calibration taken prior to patient treatment. The advantages of the present invention are particularly significant for proton therapy facilities containing a plurality of delivery systems. The method permits a prescribed treatment to be administered with accuracy not only at the station associated with the initial treatment planning, but at any available delivery station.

Normalizing and calibrating therapeutic radiation delivery systems

Growing community of inventors

Redlands, CA, United States of America

George Coutrakon