Mesoscale Technologies, Llc.

Harvard College

Methodical Mind, Llc.

Other

The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc.

Igen International, Inc.

Meso Scale Technology Llp

Meso Scale Diagnostics, LLC

Meso Sclae Technologies, Llc.

Sigal, George

Glezer, Eli N.

George B Sigal

Eli N Glezer

Jacob N Wohlstadter

Sudeep Kumar

James L Wilbur

Bandele J Jeffrey-Coker

Mark T Martin

Michael Tsionsky

Alan B Fischer

Charles M Clinton

Michael L Vock

Pankaj Oberoi

Sandor L Kovacs

Jeff D Debad

Mark A Billadeau

Larry Helms

John H Kenten

Kent Johnson

Liang-Hong Guo

Jon Leland

Carl C Stevens

Kenneth E Page

Alan Kishbaugh

Louis W Pang

Sudeep M Kumar

Jonathan K Leland

Manish Kochar

Aaron H Leimkuehler

Martin Stengelin

Anahit Aghvanyan

Kin Ng

Svetlana Leytner

Ramin Darvari

George M Whitesides

Jack L Strominger

Cynthia C Bamdad

Ian D Chamberlin

Jeffery D Debad

Sharon West

Edward J S Roques

Michael Tsionksy

Jon S Willoughby

Leo Tabakin

Gisbert Spieles

D T Le

Satyanarayana Gudibande

Selen Altunata

Michael Warnock

Anu Mathew

Kristian Roth

Natalia I Ossetrova

William F Blakely

David Routenberg

Nicholas Anderson

Stephen Higgins

Alexander K Tucker-Schwartz

Noel Lawrence

Dt Le

Jeffery Debad

Reid W Von Borstel

Jennifer Parker

Rodger Darin Osborne

Niranjan Y Sardesai

Hans Biebuyck

Eric M Jones

Peter J Bosco

Nicholas Sammons

Robert M Umek

Selen Stromgren

Jeffrey A Heroux

Victor Pellicier

Kim-Xuan Nguyen

Paula Denney Eason

Fei Yin

Xinri Cong

Gary I Krivoy

Richard C Titmas

Michael Wade

Liwen Dong

Michael Vock

Nick Sammons

Stanley Todd Smith

Stanley T Smith

Pei-Ming Wu

Don E Krueger

Eli N Glezar

Howie Tjiong

Md Athar Masood

Greg Pinckney

Lei Wang

Mike Vock

Michael T Wade

Roger D Osborne

The invention relates to novel compositions comprising an electrochemiluminescence (ECL) co-reactant. In embodiments, the composition further comprises an ionic component, a surfactant, or combination thereof. In embodiments, the ECL co-reactant is triethanolamine (TEA), tert-butyldiethanolamine (tBDEA), methyldiethanolamine (MDEA), 3-[Bis-(2-hydroxy-ethyl)-amino]-propane-1-sulfonic acid (DEA-PS), or a combination thereof. Methods of using the compositions and kits comprising the compositions are also provided herein.

Compositions and methods for assay measurements

The present invention is directed to methods for improving assay specificity and performance in binding assays.

Assay methods

A method of interactively navigating a user through a path of menu choices on a user interface may include displaying a current menu of choices on a first portion of a user interface display. The user interface allows for selecting of a menu item from the current menu of choices and to drill down through levels of menu choices based on selecting a menu item from a prior level of menu choices. A second portion of the user interface display presents past selected and past unselected menu items of the drilled-down levels. The past unselected menu items are displayed as selectable options. The user interface allows for jumping to a different path of menu choices by selecting a past unselected menu item from a previously navigated menu level displayed on the second portion of the user interface display.

Graphical user interface system

The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.

Co-binder assisted assay methods

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

Integrated consumable data management system and platform

We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.

Assay apparatuses, methods and reagents

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.

The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.

Reagent storage in an assay device

The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In embodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).

Compositions and methods for carrying out assay measurements

Provided herein are systems, methods, and apparatuses for providing a real-time global bio-surveillance and response solution. The systems and apparatuses may include one or more sentinel subsystems and one or more surge subsystems that each include a real-time, cloud-based, distributed, interconnected set of hardware, software, and/or firmware for comprehensive surveillance, complete detection, and immediate response various to biological, chemical, and/or bio-chemical anomalies, for example, a new or emerging pathogen or other health condition.

Global bio-surveillance and response system

Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.

Assay cartridges and methods of using the same

Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.

Biodosimetry panels and methods

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Rockville, MD, United States of America

George B Sigal