American Cyanamid Company

George A Chiarello

Albert A Cevasco

William F Rieker

Lawrence J Ross

There is provided a process for the preparation of dialkyl pyridinedicarboxylate compounds and derivatives thereof by reacting a dialkyl chloromaleate or chlorofumarate or a mixture thereof with an ammonium salt optionally in the presence of ammonia and an appropriately substituted .alpha.,.beta.-unsaturated aldehyde or ketone.

Process for the preparation of substituted and

There is provided a process for the preparation of substituted and unsubstituted-2,3-pyridinedicarboxylate compounds by reacting a dialkyl dichlorosuccinate with a dehydrohalogenating agent, an ammonia source and an appropriately substituted .alpha.,.beta.-unsaturated aldehyde or ketone.

Process for the preparation of dialkyl pyridine-2,3-dicarboxylate and

There is provided a process for the preparation of dialkyl pyridinedicarboxylate compounds and derivatives thereof by reacting a dialkyl chloromaleate or chlorofumarate or a mixture thereof with an ammonium salt optionally in the presence of ammonia and an appropiately substituted .alpha.,.beta.-unsaturated aldehyde or ketone.

The invention relates to a method for the denitrosation of organic nitrosamines with aliphatic and cycloaliphatic ketones or aliphatic aldehyes in the presence of a strong acid, and optionally an inert organic solvent.

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Mercer, NJ, United States of America

George A Chiarello