Kefalas A/s

Georg Ujvari

Peter Bregnedal Hansen

The present invention relates to novel xanthene and thioxanthene derivatives of the following general formula: ##STR1## wherein Y represents sulfur or oxygen, R.sup.1 represents hydrogen, chlorine, trifluoromethyl or dimethylsulfamoyl, R.sup.2 represents hydrogen or fluorine; and R.sup.3 and R.sup.4 each represents hydrogen or methyl, provided that R.sup.3 and R.sup.4 may not both represent hydrogen, or R.sup.3 and R.sup.4 taken together with the nitrogen atom form a piperazine or piperidine ring optionally substituted in the 4-position by a methyl group or a 2-hydroxyethyl group, if desired, esterified with an aliphatic carboxylic acid having from one to seventeen carbon atoms inclusive, as well as non-toxic acid addition salts thereof.

Xanthene and thioxanthene derivatives, compositions thereof and a method

The present invention relates to novel xanthene and thioxanthene derivatives of the following general formula: ##STR1## wherein Y represents sulfur or oxygen, R.sup.1 represents hydrogen, chlorine, trifluoromethyl or dimethylsulfamoyl,

Xanthene and thioxanthene compositions and method of treating

The present invention relates to novel xanthene and thioxanthene derivatives of the following general formula: ##SPC1## Wherein Y represents sulfur or oxygen, R.sup.1 represents hydrogen, chlorine, trifluoromethyl or dimethylsulfamoyl, R.sup.2 represents hydrogen or fluorine; and R.sup.3 and R.sup.4 each represents hydrogen or methyl, provided that R.sup.3 and R.sup.4 may not both represent hydrogen, or R.sup.3 and R.sup.4 taken together with the nitrogen atom form a piperazine or piperidine ring optionally substituted in the 4-position by a methyl group or a 2-hydroxyethyl group, if desired, esterified with an aliphatic carboxylic acid having from 1 to 17 carbon atoms inclusive, as well as non-toxic acid addition salts thereof.

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Nykobing S, Denmark

Georg Ujvari