E.i. Dupont De Nemours and Company

Geoffrey B Cox

Anthony Atkinson

Robert K Kobos

Richard Wayne Stout

Michael D Scawen

Peter A Edwardson

A solid support useful for bioaffinity and ion-exchange separations and enzyme immobilization is provided. The support is based on a non-perfluorocarbon solid carrier core coated with a nonionic fluorosurfactant-coated fluorocarbon interlayer to which a ligand or a binder for the ligand is securely, but reversibly attached through a reactive perfluorocarbon anchor compound. Also provided is a solid support useful for size exclusion separations. Such support is based on a non-perfluorocarbon carrier core coated with a nonionic fluorosurfactant-coated fluorocarbon interlayer.

Fluorocarbon polymer support for chromatographic separations, diagnostic

The porosity of a porous silica body is increased in a controlled manner by contacting the body with an effective amount of ammonium bifluoride.

Process for porosity control and rehydroxylations of silica bodies

A chromatographic packing useful for the separation of oligonucleotides is disclosed. The packing includes an insert porous support particle and a silane bonded phase comprising a weak anion exchange group in close proximity to at least one polar non-ionic group.

Growing community of inventors

Wilmington, DE, United States of America

Geoffrey B Cox