Abbvie Inc.

Geoff T Halvorsen

Rolf Wagner

John T Randolph

Allan C Krueger

David A DeGoey

Yi-Yin Ku

Tongmei Li

Eric A Voight

Hui-Ju J Chen

John Hartung

Christopher C Marvin

Vikram Kalthod

Jaclyn Chau

Nathan Ide

Philip R Kym

Jennifer M Frost

Brian S Brown

Howard Robin Heyman

Anurupa Shrestha

Steven R Martinez

Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.

Protein tyrosine phosphatase inhibitors and methods of use thereof

The present invention features compounds effective in inhibiting active against Hepatitis C virus ('HCV') polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Anti-viral compounds

Growing community of inventors

Lake Bluff, IL, United States of America

Geoff T Halvorsen